TGen investigators devise faster, cheaper way of analyzing the human genome

sea-maid submitted, created time 3 months 3 weeks (esciencenews.com)

Investigators at the Translational Genomics Research Institute (TGen) today announced a faster and less expensive way for scientists to find which genes might affect human health.

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caGEDA: a web application for the integrated analysis of global gene expression patterns in cancer.

Lateral gene transfer between obligate intracellular bacteria: Evidence from the Rickettsia massiliae genome

angelfish submitted, created time 1 year 2 months (www.genome.org)

"Researchers demonstrate that the tra region was acquired recently by lateral gene transfer (LGT) from a species related to Rickettsia bellii. Further analysis of the genomic sequences identifies additional candidates of LGT between Rickettsia. This study indicates that recent LGT between obligate intracellular Rickettsia is more common than previously thought. "

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Scientists identify gene related to heart disease

Darkfrog submitted, created time 1 year 8 months (www.nytimes.com)

Not that the rest of us should chow down on cheeseburgers... Two separate (and nearly simultaneous) studies have identified an allele on the ninth chromosome that ups the risk of heart disease by 15-20% in heterozygotes and up to 60% in homozygotes. This gene variant is so common that half of the people in Europe have one copy and one-fifth have two.

So the question is this: Why? Does this gene convey some backhanded evolutionary advantage like sickle-cell anemia or does it just age out of natural selection like Huntington's Disease?

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Gene Analysis Might Explain Ethnic Differences In Sensitivity To Chemotherapy In Lung Cancer

dovechocolate submitted, created time 1 year 8 months (www.sciencedaily.com)

Analysis of three genetic mechanisms that cause non-small cell lung cancer might explain why East Asians respond better than other ethnic groups to a certain type of chemotherapy, a team led by UT Southwestern Medical Center researchers has found.

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