Articles with the keyword: 


Oxygen Key To 'Cut And Paste' Of Genes
sea-maid submitted, created time 1 year 1 month (www.sciencedaily.com)
An oxygen-sensitive enzyme has been found to play a key role in how genes create the many different proteins that make up our bodies. 


Autism genes discovered; help shape connections among brain cells
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
A research team has connected more of the intricate pieces of the autism puzzle, with two studies that identify genes with important contributions to the disorder. One study pinpoints a gene region that may account for as many as 15 percent of autism cases, while another study identifies missing or duplicated stretches of DNA along two crucial gene pathways. Significantly, both studies detected genes implicated in the development of brain circuitry in early childhood 


Researchers find possible genetic link for pelvic floor disorders
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
University of Utah researchers have identified a region of the human genome that may contribute to the development of pelvic floor disorders such as pelvic organ prolapse and stress urinary incontinence, according to a study published this week in the American Journal of Human Genetics.
Kristina Allen-Brady, Ph.D., and her colleagues at the University of Utah School of Medicine analyzed the DNA of seventy women from thirty-two families with at least two cases of pelvic floor disorders (PFD) and found significant evidence that a gene on chromosome 9 predisposes patients to PFD 


Researchers discover that gene switches on during development of epilepsy
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
A discovery made by researchers at Wake Forest University School of Medicine while studying mice may help explain how some people without a genetic predisposition to epilepsy can develop the disorder.
In a study published this month in the Journal of Neuroscience, senior researcher Dwayne W. Godwin, Ph.D 


Study identifies genes that protect against aging
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
Scientists at the University of Liverpool have developed a new method to help researchers identify genes that can help protect the body during the aging process.
The team developed a method of analyzing genes in several types of aging tissue in both animals and humans. The analysis, which included more than five million gene measurements, highlighted the mechanisms used by the body to protect against age-related cellular changes that can result in muscle degeneration and cognitive aging 


piggy submitted, created time 1 year 4 months (www.eurekalert.org)
A collaboration between more than seventy researchers across the globe has uncovered nine new genes on the X chromosome that, when knocked out, lead to learning disabilities. This international team studied almost all the X chromosome genes in 208 families with learning disabilities--the largest screen of this type ever reported.
Remarkably, the team also found that approximately 1% of X chromosome genes have no apparent effect on an individual's ability to function in the ordinary world 


At Risk for Kidney Disease? Check Your Genes
sea-maid submitted, created time 1 year 4 months (www.sciencedaily.com)
Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease (CKD), according to a new study. The results may be important for determining patients' health risks and for devising new medical treatments. 


Conserved Gene Expression Reveals Our Inner Fish
sea-maid submitted, created time 1 year 4 months (www.sciencedaily.com)
A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues. Researchers have shown that expression in tissues with a limited number of specialized cell types is strongly conserved, even between the mammalian and non-mammalian vertebrates. 


Scientists discover genetic variant tied to increased stroke risk
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
Millions of people have a genetic variant linked to increased risk of ischemic stroke, reports an international research team including scientists at the University of Texas Health Science Center at Houston. The study was published online by the New England Journal of Medicine on April 15.
Ischemic stroke accounts for nearly ninety percent of all strokes and is caused by blockage of blood to the brain. More than 150,000 Americans succumb to stroke every year, making it the third leading cause of death. Survivors often experience permanent stoke-related disabilities. 


Penn biologists discover how silent mutations influence protein production
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
Biologists at the University of Pennsylvania have revealed a hidden code that determines the expression level of a gene, providing a way to distinguish efficient genes from inefficient ones. The new research, which involved creating hundreds of synthetic green-glowing genes, provides an explanation for how a cell "knows" how to make just the right amount of protein to maintain homeostasis yet not so much as to cause cell toxicity 


Ten genes identified in connection with sudden cardiac death
piggy submitted, created time 1 year 5 months (www.eurekalert.org)
You're sitting at your desk and suddenly your heart is beating in overdrive or worse, lurching along like a car on fumes. It is a shocking, uncomfortable and frightening sensation.
Irregular heart rhythms are a common cause of sudden cardiac death or SCD, a condition that accounts for 450,000 deaths annually in the United States. Scientists are now closer to understanding what causes SCD and who it may strike, said Gonçalo Abecasis, associate professor of biostatistics at the University of Michigan School of Public Health 


Researchers identify a process that regulates seed germination
piggy submitted, created time 1 year 5 months (news.uns.purdue.edu)
Purdue University researchers have determined a process that regulates activity of genes that control seed germination and seedling development.
Mike Hasegawa, the Bruno C. Moser Distinguished Professor of Horticulture and Landscape Architecture, and Kenji Miura, a former Purdue postdoctoral researcher and now an assistant professor at Tsukuba University in Japan, discovered the step involved in keeping seeds from germinating in adverse conditions such as freezing temperatures or drought, a factor in the survival of plant species. 


The Genetics of Fear: Study Suggests Specific Genetic Variations Contribute to Anxiety Disorders
piggy submitted, created time 1 year 5 months (www.psychologicalscience.org)
Polymorphisms are variations in genes which can result in changes in the way a particular gene functions and thus may be associated with susceptibility to common diseases. In a new study in Psychological Science, a journal of the Association for Psychological Science, psychologist Tina B. Lonsdorf and her colleagues from the Karolinska Institutet in Sweden and the University of Greifswald in Germany examined the effect of specific polymorphisms on how fear is learned and how that fear is subsequently overcome 


Genetic test predicts eye color
sea-maid submitted, created time 1 year 5 months (www.nature.com)
Police might soon be able to use DNA recovered from crime scenes to determine the eye color of the suspect who left it behind, thanks to a new genetic study. ...specifically, criminals in the Netherlands and nowhere else. In addition, the test is only 80% effective, which criminalists say is not high enough to be practical in the field.
There are some concerns that this test, in combination with PGD, might be used by parents to select the eye color of their children. 


A Curious Case of Genetic Resurrection
piggy submitted, created time 1 year 5 months (sciencenow.sciencemag.org)
Some genes just won't stay dead. Between 40 million and 50 million years ago, a slice of DNA called IRGM stopped functioning in the ancestors of modern-day monkeys. But 25 million years later, in the lineage that led to humans and great apes, three random events turned the gene back on.
In mammals such as rats and dogs, IRGM (immunity-related GTPase family, M) helps protect from bacterial pathogens such as salmonella. Humans and apes also appear to use the gene 