Articles with the keyword: 
HIV gene is a mixed blessing for carriers
sea-maid submitted, created time 4 months 1 week (www.newscientist.com)
A GENETIC mutation common in African Americans slows the progression of HIV, yet paradoxically increases the risk of contracting the virus in the first place.
A clue that race-specific genes are involved in HIV came in 2002, when Sunil Ahuja of the University of Texas Health Science Center in San Antonio and colleagues discovered a mutation in the CCL5 gene that accelerates the progression of HIV-1, the most common form of the virus. Though the mutation was found in people of all races, it only accelerated the disease in Americans of European descent 
Genomic medicine sector "needs government backing"
kavin submitted, created time 4 months 3 weeks (www.scidev.net)
Government support, strong leadership within institutions and the protection of "genomic sovereignty" are vital to the burgeoning genomic medicine sector in developing countries, say researchers.
Some developing countries are starting to use genomic science, aiming both for public health benefits and to produce knowledge to stimulate their economies. They often do this by setting up large-scale genotyping projects to assess susceptibility to disease
jerry submitted, created time 6 months 2 days (www.sciencedaily.com)
Researchers have determined the DNA sequence of a woman. She is also the first European whose DNA sequence has been determined...
Thousands of genomes exist in a giant bacterium
sea-maid submitted, created time 6 months 2 weeks (www.nature.com)
This study tell us about a single-celled bacterium that has been found to keep tens of thousands of copies of its genome.
New strategy could describe outbreak strains rapidly
sea-maid submitted, created time 6 months 3 weeks (www.genome.org)
This report, which is published online in Genome Research, demonstrates a new approach using next-generation sequencing technology to identify unique genetic properties of a potential outbreak strain quickly. High-throughput sequencing technology and the comparative genomic analysis strategy outlined in this work have significantly decreased the time required for characterization of an outbreak strain.
The similarity between human and fly
Sue Wu submitted, created time 8 months 1 week (www.sciencedaily.com)
According to researchers at the Monell Center, fruit flies are more like humans in their responses to many sweet tastes than are almost any other species.
Dynamics of Pseudomonas aeruginosa genome evolution
davidd submitted, created time 9 months 1 day (www.pnas.org)
One of the hallmarks of the Gram-negative bacterium Pseudomonas aeruginosa is its ability to thrive in diverse environments that includes humans with a variety of debilitating diseases or immune deficiencies. Here they report the complete sequence and comparative analysis of the genomes of two representative P. aeruginosa strains isolated from cystic fibrosis (CF) patients whose genetic disorder predisposes them to infections by this pathogen.
China gene experts search for answers on diabetes
sumsung submitted, created time 9 months 6 days (www.reuters.com)
Chinese scientists are trying to find out which errant genes are responsible for diabetes and certain forms of cancer that have long plagued Chinese populations, a geneticist said. Rising affluence, richer diets and a sedentary lifestyle have led to an alarming rise in cases of diabetes in China in recent decades, while cancers of the esophagus, lungs, breast, stomach and colon have plagued Chinese people for a much longer time.
Company claims to have sequenced man's genome cheaply
Sue Wu submitted, created time 9 months 3 weeks (www.nature.com)
A company based in San Diego, California, claims to have sequenced an individual human genome cheaper and faster than ever before.
Reasearchers appeal to the private sector: Please sequence my eel!
Darkfrog submitted, created time 9 months 3 weeks (www.nature.com)
This is not the first time that cash-strapped researchers have gone on a mission of whining so that someone else will shell out the $10 million that it can take for a full organism genome to be sequenced. Someone actually convinced a backer that the tammer wallaby would be a good idea (I kid; the tammer wallaby is actually a model organism for some forms of research), but the electric eel, although technically not a member of that most tasty-when-broiled family, the true eels, is surely one of the most interesting.
Sifting the Genome for Clues to Cancer
sumsung submitted, created time 9 months 4 weeks (sciencenow.sciencemag.org)
Biologists have hunted for weak spots in cancer cells for years, hoping to find clues to the disease that can be exploited. That should get easier thanks to a mass-screening technique reported in the 1 February issue of Science that may provide a cost-effective and powerful way to pick out new drug targets against cancer.
"Normal" genes key to cancer growth
jane2007 submitted, created time 10 months 19 hours (www.nature.com)
Geneticists have identified genes that are normally present and that seem to be key to the growth and survival of specific cancers. The finding, from a functional-genomics screen of human cells, could offer new drug targets for blitzing tumors.
Genome stitched together by hand
sumsung submitted, created time 10 months 6 days (www.nature.com)
Scientists have succeeded in stitching together an entire bacterial genome, creating in the lab the full set of instructions needed to make a living thing. The stage is now set for the creation of the first artificial organism — and it could be achieved within the year.
Scientists Synthesize a Genome From Scratch
sumsung submitted, created time 10 months 6 days (sciencenow.sciencemag.org)
Researchers have rebuilt an entire genome from scratch, they report online today in Science. Although the team has yet to demonstrate that this DNA can substitute for the real thing, the work paves the way for customized bacteria that could efficiently produce drugs, biofuels, and other molecules useful to humankind.
A code for transcription initiation in mammalian genomes
Charles submitted, created time 10 months 1 week (www.genome.org)
Genome-wide detection of transcription start sites (TSSs) has revealed that RNA Polymerase II transcription initiates at millions of positions in mammalian genomes. Most core promoters do not have a single TSS, but an array of closely located TSSs with different rates of initiation. As a rule, genes have more than one such core promoter; however, defining the boundaries between core promoters is not trivial. These discoveries prompt a re-evaluation of our models for transcription initiation. We describe a new framework for understanding the organization of transcription initiation.
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