A Viral Link to Glioblastoma

sea-maid submitted, created time 1 day 1 hour (www.sciencemag.org)

Circumstantial evidence hints that the cytomegalovirus, a common herpes virus, may play a role in aggressive brain cancer, but big questions remain.

1 comment | Blog It | Email It | Keywords: viruses cytomegalovirus brain cancer cancer Glioblastoma

GUMC researchers find gene function "lost" in melanoma and glioblastoma

piggy submitted, created time 3 weeks 2 days (www.eurekalert.org)

Researchers at Georgetown University Medical Center have found a gene they say is inactivated in two aggressive cancers – malignant melanoma, a form of skin cancer, and glioblastoma multiforme, a lethal brain tumor. They add that because this gene, known as PTPRD, has recently been found to be inactivated in several other cancers as well, their discovery suggests that PTPRD may play a tumor suppressor role in a wide variety of different cancers.

The findings are published in the December 15 issue of Cancer Research

1 comment | Blog It | Email It | Keywords: glioblastoma genes genetics melanoma cancer tumors tumor suppressor genes tumor suppressors PTPRD

Major Breakthrough in Cancer Research

jerry submitted, created time 3 months 4 weeks (www.efluxmedia.com)

By Alice Carver Scientists with the Johns Hopkins Kimmel Cancer Center at the Johns Hopkins University have managed to draw a map of the genetic mutations involved in two of the most aggressive cancers: glioblastoma, the most common form of brain.

1 comment | Blog It | Email It | Keywords: brain cancer glioblastoma gene mapping cancer research cancer

Genome analysis used to decode brain cancer: study

sea-maid submitted, created time 4 months 22 hours (afp.google.com)

U.S. scientists have unveiled the most complete genetic profile ever attempted of glioblastoma, a common and deadly form of the brain cancer that U.S. Senator Edward Kennedy is battling.

Submit comment | Blog It | Email It | Keywords: cancer oncology glioblastoma Cancer Genome brain cancer therapy

Radiotherapy for Glioblastoma in the Elderly

collapsar submitted, created time 1 year 8 months (content.nejm.org)

"There is no community standard for the treatment of glioblastoma in patients 70 years of age or older. We conducted a randomized trial that compared radiotherapy and supportive care with supportive care alone in such patients. Patients 70 years of age or older with a newly diagnosed anaplastic astrocytoma or glioblastoma and a Karnofsky performance score of 70 or higher were randomly assigned to receive supportive care only or supportive care plus radiotherapy (focal radiation in daily fractions of 1.8 Gy given 5 days per week, for a total dose of 50 Gy)

Submit comment | Blog It | Email It | Keywords: Radiotherapy glioblastoma elder people