'Painkiller' gene turned off in mice

Eric wu submitted, created time 1 year 2 weeks (www.newscientist.com)

Mice lacking a key protein took longer to react to a painful stimulus, prompting hopes for a new class of painkillers

1 comment | Blog It | Email It | Keywords: mouse model painkillers pain management anesthesiology pain gnotobiotic mice protein-coding gene

U.S. researchers create schizophrenic mice

Reviver submitted, created time 1 year 5 months (www.reutershealth.com)

U.S. Scientists have genetically engineered mice ,they said the finding will help improve understanding of the disease and help develop drugs to treat it that will develop the physical and psychological characteristics of schizophrenia.

3 comments | Blog It | Email It | Keywords: disease Psychology gnotobiotic mice

Genomic and metabolic adaptations of Methanobrevibacter smithii to the human gut

addict submitted, created time 1 year 6 months (www.pnas.org)

The human gut is home to trillions of microbes, thousands of bacterial phylotypes, as well as hydrogen-consuming methanogenic archaea. Studies in gnotobiotic mice indicate that Methanobrevibacter smithii, the dominant archaeon in the human gut ecosystem, affects the specificity and efficiency of bacterial digestion of dietary polysaccharides, thereby influencing host calorie harvest and adiposity

Submit comment | Blog It | Email It | Keywords: archaeal-bacterial mutualism comparative microbial genomics functional genomics and metabolomics gnotobiotic mice human gut microbiota