The benefits of green tea in reducing an important risk factor for heart disease

kavin submitted, created time 4 months 2 weeks (esciencenews.com)

More evidence for the beneficial effect of green tea on risk factors for heart disease has emerged in a new study reported in the latest issue of European Journal of Cardiovascular Prevention and Rehabilitation.1 The study found that the consumption of green tea rapidly improves the function of (endothelial) cells lining the circulatory system; endothelial dysfunction is a key event in the progression of atherosclerosis

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Green tea selectively targets initial stages of intestinal carcinogenesis in the AOM-ApcMin mouse model

jiangyun submitted, created time 1 year 2 months (carcin.oxfordjournals.org)

One of the liabilities of the ApcMin mouse as a model for colon cancer is its lack of a robust tumor response in the large bowel. In our protocol, we treated the ApcMin mouse with azoxymethane (AOM), a colon selective carcinogen. This protocol induced a 4-fold increase in the number of colon tumors. We utilized this protocol to investigate the possible mechanisms of inhibition of colorectal carcinogenesis by green tea (GT).

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Green tea holds promise as new treatment for inflammatory skin

Reviver submitted, created time 1 year 3 months (news.xinhuanet.com)

U.S. researchers reported Tuesday that the properties of green tea might offer a new treatment for skin disorders such as psoriasis and dandruff.

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Green tea holds promise as new treatment for inflammatory skin diseases

MedColGa submitted, created time 1 year 3 months (www.discover8.com)

Green tea could hold promise as a new treatment for skin disorders such as psoriasis and dandruff, Medical College of Georgia researchers say.

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Green tea can be harmful in large quantities

fiona submitted, created time 1 year 6 months (www.newscientist.com)

"Green tea is good for you, but only if drunk in moderation. While the polyphenols in green tea are credited with preventing heart disease and cancer, it seems they can cause liver and kidney damage if consumed in very large quantities, a review of studies into the toxicity of polyphenols has shown."

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Green Tea Compound May Be A Therapy For Rheumatoid Arthritis

collapsar submitted, created time 1 year 6 months (www.medicalnewstoday.com)

A compound in green tea may provide therapeutic benefits to people with rheumatoid arthritis. The study, presented April 29 at the Experimental Biology 2007 in Washington, D.C., looks at a potent anti-inflammatory compound derived from green tea. Researchers found that the compound called epigallocatechin-3-gallate (EGCG) inhibited the production of several molecules in the immune system that contribute to inflammation and joint damage in people with rheumatoid arthritis.

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Green Tea May Help Prevent Autoimmune Diseases

diggman submitted, created time 1 year 6 months (www.medicalnewstoday.com)

Researchers studied an animal model for type I diabetes and primary Sjogren's Syndrome, which damages the glands that produce tears and saliva. They found significantly less salivary gland damage in a group treated with green tea extract, suggesting a reduction of the Sjogren's symptom commonly referred to as dry mouth. Dry mouth can also be caused by certain drugs, radiation and other diseases.

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SHP-2 tyrosine phosphatase inhibits p73-dependent apoptosis and expression of a subset of p53 target genes induced by EGCG

psychologist submitted, created time 1 year 7 months (www.pnas.org)

"Green tea polyphenol, epigallocatechin-3-gallate (EGCG) differentially regulates the cellular growth of cancer cells in a p53-dependent manner through apoptosis and/or cell cycle arrest. In an effort to further elucidate the mechanism of differential growth regulation by EGCG, we have investigated the role of the tyrosine phosphatase, SHP-2. Comparing the responses of mouse embryonic fibroblasts (MEFs), expressing either WT or functionally inactive/truncated SHP-2, we find that inactivation of SHP-2 remarkably sensitizes cells to EGCG-mediated killing

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