Articles with the keyword: 


sea-maid submitted, created time 6 days 7 hours (www.time.com)
Fish oil supplements may work slightly better than a popular cholesterol-reducing drug to help patients with chronic heart failure 


Fish Oil Supplements Help With Heart Failure
jerry submitted, created time 6 days 21 hours (www.washingtonpost.com)
Daily supplements of omega-3 polyunsaturated fatty acids -- the kind found in fish oil -- reduced deaths and hospitalizations of people with heart failure, an Italian study found. 


Increased Mortality after Dronedarone Therapy for Severe Heart Failure
kavin submitted, created time 2 months 5 days (content.nejm.org)
Background: Dronedarone is a novel antiarrhythmic drug with electrophysiological properties that are similar to those of amiodarone, but it does not contain iodine and thus does not cause iodine-related adverse reactions. Therefore, it may be of value in the treatment of patients with heart failure.
Methods: In a multicenter study with a double-blind design, we planned to randomly assign 1000 patients who were hospitalized with symptomatic heart failure and severe left ventricular systolic dysfunction to receive 400 mg of dronedarone twice a day or placebo 
davidd submitted, created time 4 months 2 weeks (sciencenow.sciencemag.org)
Scientists have discovered a genetic mutation that could explain why clinical trials of beta blockers have shown little benefit to African-American patients. Beta blockers block adrenaline receptors and slow heart rate, which can ease heart failure. 


Government posts US hospital death rates for heart ailments
Reviver submitted, created time 1 year 2 months (www.reutershealth.com)
"The government posted mortality data on Thursday for the nation's thousands of hospitals for heart attacks and heart failure, in an effort to shed light on which hospitals provide the best care." 


US Scores Hospitals on Heart Care
bioman submitted, created time 1 year 2 months (www.examiner.com)
The government gave hospitals around the country a public report card Thursday that measures their performance in the treatment of patients suffering from heart attacks or heart failure. 


Low Potassium Levels Linked To Increased Long-Term Mortality In Heart Failure Patients
deirdre submitted, created time 1 year 2 months (www.sciencedaily.com)
New research from University of Alabama at Birmingham indicates that patients with heart failure who have low to low-normal serum potassium levels are at increased risk of death. The study, published in the European Heart Journal, is the first to look directly at the long-term effect of low potassium levels in a population of propensity-matched heart failure patients. 


Heart Failure In Animals Reversed Using Gene Therapy
psychologist submitted, created time 1 year 3 months (www.medicalnewstoday.com)
Scientist used a virus to carry the gene for a protein, S100A1, into the heart cells of rats with heart failure. The virus expressed the S100A1 gene only in heart cells and not in other organs, essentially making it a tailored therapy. After 18 weeks, those animals that received the gene therapy had significantly improved heart function compared to animals that did not receive the treatment. 


fiona submitted, created time 1 year 3 months (eurheartj.oxfordjournals.org)
"Detailed analysis of the myocardial contraction sequence using circumferential strain imaging allows determination of the LV lead position in CRT. Optimal LV lead position in CRT defined by circumferential strain analysis results in greater improvement in LV function and more LV reverse remodelling than non-optimal LV lead position. " 


Myocardial production of chromogranin A in human heart: a new regulatory peptide of cardiac function
amanda submitted, created time 1 year 3 months (eurheartj.oxfordjournals.org)
"We demonstrate for the first time that CgA is produced by human myocardium and exerts negative inotropic and lusitropic effects on mammalian heart. CgA may represent a key player in neuroendocrine regulation of cardiac function and a potential therapeutic target in heart failure. " 


Cardiac Resynchronization Treatment of Heart Failure
big pig submitted, created time 1 year 3 months (arjournals.annualreviews.org)
"Cardiac resynchronization therapy (CRT) is well established as a treatment for patients with moderate to severe heart failure on optimal medical therapy. Early studies demonstrated improved functional capacity and evidence of reverse remodeling; more recently, CRT has been associated with a survival benefit in advanced heart failure both with and without a defibrillator. We review the eight landmark trials in CRT. To date, criteria have focused on electrical delay, but echocardiographic parameters emphasize the importance of mechanical delay or ventricular dyssynchrony 


Percutaneous aortic valve replacement safe, successful in high-risk patients
amanda submitted, created time 1 year 3 months (www.biologynews.net)
"Catheter techniques are expanding into new territory, successfully aiding in the replacement of narrowed, calcified aortic valves in patients too sick to withstand open-chest surgery. According to a study reported at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions (SCAI), May 9–12, 2007, in Orlando, FL, patients who were treated with the CoreValve Revalving System (CoreValve, Irvine, CA) experienced improvements in both the size of the aortic valve and in the severity of heart failure. " 


The potential of cardiac stem cell therapy for heart failure
medal submitted, created time 1 year 4 months (www.sciencedirect.com)
"Cardiac failure is characterised by the loss of cardiomyocytes, and several strategies to replace the lost cell mass are being developed. Animal models have demonstrated the therapeutic potential of several cell types, and both autologous skeletal myoblasts and bone marrow progenitor cells have been tested in preliminary clinical trials. However functional improvements have been modest and the mechanism of benefit is unclear, although myocardial regeneration is not a significant factor 


julie submitted, created time 1 year 4 months (circ.ahajournals.org)
"Identification of heart failure outpatients at increased risk for clinical deterioration remains a critical challenge, with few tools currently available to assist clinicians. We tested whether serial health status assessments with the Kansas City Cardiomyopathy Questionnaire (KCCQ) can identify patients at increased risk for mortality and hospitalization. " 


Too Much Energy Can Lead To Heart Failure
channel submitted, created time 1 year 4 months (www.medicalnewstoday.com)
The amount of energy available to a cell is controlled by the protein AMPK, which senses when a cell has low levels of energy and triggers the cell to generate more. Mutations in one of the AMPK subunits (gamma-2) leading to increased AMPK activity are associated with heart failure characterized by the accumulation of high levels of the energy source glycogen in heart muscle cells. 