Articles with the keyword: 
Hearing test may spot babies at risk for SIDS
DanyC submitted, created time 1 year 4 months (www.reutershealth.com)
A disruption of the function of the inner ear may interfere with not only hearing but also with a baby's control of breathing during sleep, the researchers explain in the medical journal Early Human Development. 
DNA Computer Works in Human Cells
julie submitted, created time 1 year 7 months (www.sciam.com)
"Researchers have designed a new type of DNA computer that works in human cells, perhaps paving the way for a distant technology capable of picking out diseased cells from otherwise healthy tissue. The system runs on a process called RNA interference (RNAi) in which small molecules of RNA prevent a gene from producing protein. "
Speeding 'fingertip' discovery -- 20 years of protein info in 1 place
athena submitted, created time 1 year 8 months (www.biologynews.net)
"Researchers at Johns Hopkins took advantage of a new technique that reads the makeup of proteins to identify nearly all chemical changes nature makes by adding phosphate to proteins manufactured in human cells. ”
captainclaw submitted, created time 1 year 10 months (www.mcponline.org)
“Study demonstrated that IL-4 decreases expression of Fas receptor and increases expression of Bid, Bcl-2, and Bcl-xL. Importantly IL-4 significantly up-regulated the short form of c-FLIP, although the levels of c-FLIP long were unaltered after IL-4 induction. Taken together, our results indicate that IL-4 inhibits caspase activity during the initial stages of human Th2 cell differentiation by regulating expression of several key players in the Fas-induced pathway.”
Large-scale identification of novel transcripts in the human genome.
saury submitted, created time 1 year 10 months (www.genome.org)
“Although the sequencing of the human genome has been completed, the number and identity of genes contained within it remains to be fully determined. LongSAGE is used to analyze 660,357 human transcripts from human brain mRNA and identified expression of 17,409 known genes and >15,000 different transcripts that were not annotated in genome databases. Analysis of a subset of these unannotated transcripts suggests that 85% were differentially expressed in various tissue types and that fewer than 20% would have been detected by ab initio gene predictions
California gets go-ahead on stem cell research
Darkfrog submitted, created time 1 year 10 months (www.nytimes.com)
Both anti-stem cell and anti-taxation groups took the State of California to court over its generous grant of $3 billion to human embryonic stem cell research. Even though the state made the decision years ago, the first grants didn't go out until early February. The California Court of Appeals, based in San Francisco, has upheld the state's decision.
New discover of structures of the Cd44–hyaluronan complex
nomad submitted, created time 1 year 10 months (www.nature.com)
Regulation of transient interactions between cells and the ubiquitous matrix glycosaminoglycan hyaluronan is crucial to such fundamental processes as embryonic development and leukocyte homing. Cd44, the primary cell surface receptor for hyaluronan, binds ligand via a lectin-like fold termed the Link module, but only after appropriate functional activation. The molecular details of the Cd44-hyaluronan interaction and hence the structural basis for this activation are unknown. Here we present the first crystal structure of Cd44 complexed with hyaluronan
Epigenetic stem cell signature in cancer
nomad submitted, created time 1 year 10 months (www.nature.com)
Embryonic stem cells rely on Polycomb group proteins to reversibly repress genes required for differentiation. We report that stem cell Polycomb group targets are up to 12-fold more likely to have cancer-specific promoter DNA hypermethylation than non-targets, supporting a stem cell origin of cancer in which reversible gene repression is replaced by permanent silencing, locking the cell into a perpetual state of self-renewal and thereby predisposing to subsequent malignant transformation.
New rules is coming for stem cell research
captainclaw submitted, created time 1 year 10 months (www.newscientist.com)
Its guidelines also diverge from those of the NAS regarding the creation of chimeras by injecting animals with human embryonic stem cells. Both the NAS and the ISSCR outlaw the mating of adult chimeras with each other, as this could accidentally create a human embryo inside an animal. The NAS guidelines also oppose the mating of chimeras with non-chimeras, and while the ISSCR calls for a strict local review of these kinds of experiments it does not rule them out
New cancer treatments will come
annatto submitted, created time 1 year 11 months (www.sciencedaily.com)
researchers say they have discovered a new method of controlling cell growth, possibly leading to new targets for cancer treatments. This discovery not only adds to our basic understanding of cell division, it could lead to better cancer drugs. Since cell growth is a fundamental biological process.
Human Diabetes Will Get a Exit
angelfish submitted, created time 1 year 11 months (www.newscientist.com)
In people with type 1 diabetes, the islet cells of the pancreas do not produce enough insulin to regulate blood glucose effectively. The standard treatment is insulin injections. but there is a shortage of donors and the procedure can cost $300,000 per patient.
Now a treatment for type 1 diabetes that involves injecting pig cells into human patients is about to be trialled in Russia. This is a very reasonable line of investigation. The researchers say the treatment could provide a much cheaper, patients should not need to take immunosuppressants
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