Dominant Inhibition of Fas Ligand-Mediated Apoptosis due to a Heterozygous Mutation Associated with Autoimmune Lymphoproliferative Syndrome (ALPS) Type Ib

Reviver submitted, created time 1 year 6 months (www.biomedcentral.com)

“This data explain how a naturally occurring heterozygous human FasL mutation can dominantly interfere with normal FasL apoptotic function and lead to an ALPS phenotype, designated Type Ib.”

Submit comment | Blog It | Email It | Keywords: Type Ib human immunodeficiency virus type 1 BRCA mutation

Usefulness of Herpes Consensus PCR methodology to routine diagnostic testing for herpesviruses infections in clinical specimens

angelfish submitted, created time 1 year 6 months (www.virologyj.com)

"The purposes of the study were to assess the usefulness of simultaneously amplifying herpes simplex virus 1 and 2, varicella-zoster virus, cytomegalovirus, Epstein-Barr virus and human herpesvirus 6 DNA in various clinical specimens and to analyze clinical events in patients presenting positive results

Submit comment | Blog It | Email It | Keywords: Epstein Barr Virus (EBV) human immunodeficiency virus type 1 varicella-zoster virus human herpesvirus 6 DNA

Our upright walking started in the tree

Reviver submitted, created time 1 year 7 months (www.aidsrestherapy.com)

"During the extended clinically latent period associated with Human Immunodeficiency Virus (HIV) infection the virus itself is far from latent. This phase of infection generally comes to an end with the development of symptomatic illness. Understanding the factors affecting disease progression can aid treatment commencement and therapeutic monitoring decisions. An example of this is the clear utility of CD4 count and HIV-RNA viral load for disease stage and progression assessment

Submit comment | Blog It | Email It | Keywords: human skin disease EKV human immunodeficiency virus type 1 HIV disease treatment