Adult stem cells from human cord umbilical cord blood successfully engineered to make insulin

alpha submitted, created time 1 year 7 months (www.biologynews.net)

"In a fundamental discovery that someday may help cure type 1 diabetes by allowing people to grow their own insulin-producing cells for a damaged or defective pancreas, medical researchers here have reported that they have engineered adult stem cells derived from human umbilical cord blood to produce insulin."

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Nephrin Is Critical for the Action of Insulin on Human Glomerular Podocytes

athena submitted, created time 1 year 8 months (diabetes.diabetesjournals.org)

"The leading causes of albuminuria and end-stage renal failure are secondary to abnormalities in the production or cellular action of insulin, including diabetes and hyperinsulinemic metabolic syndrome. The human glomerular podocyte is a critical cell for maintaining the filtration barrier of the kidney and preventing albuminuria."

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Adding Insulin Glargine Versus Rosiglitazone

athena submitted, created time 1 year 8 months (care.diabetesjournals.org)

"Although addition of insulin glargine and rosiglitazone achieved comparable improvements in glycemic control, insulin glargine was associated with greater improvements in HRQOL, indicating that other factors (e.g., safety profile and nonglycemic actions) may further enhance HRQOL in patients with type 2 diabetes. "

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Maternal Glycemic Control and Hypoglycemia in Type 1 Diabetic Pregnancy

amanda submitted, created time 1 year 9 months (care.diabetesjournals.org)

"IAsp is at least as safe and effective as HI when used in basal-bolus therapy with NPH insulin in pregnant women with type 1 diabetes and may potentially offer some benefits in terms of postprandial glucose control and preventing severe hypoglycemia. "

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