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Breaking out new ideas on molting

kavin submitted, created time 5 months 3 days (www.jcb.org)

Alison Frand believes that understanding the molting process of the nematode worm, C. elegans, might provide new insights into diseases affecting humans. Some of the potential medical benefits lie in the similarities between the worms' exoskeleton and our own skin and connective tissues, while other benefits might lie in the unique aspects of worm molting. Alison Frand is using RNAi, GFP-PEST, and other state-of-the-art tools to study molting in worms.

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Atopic Dermatitis

Vincent submitted, created time 7 months 2 weeks (content.nejm.org)

Atopic dermatitis, or eczema, is a common skin disease that is often associated with other atopic disorders, such as allergic rhinitis and asthma 1. The clinical manifestations of atopic dermatitis vary with age; three stages can often be identified. In infancy, the first eczematous lesions usually emerge on the cheeks and the scalp. Scratching, which frequently starts a few weeks later, causes crusted erosions. During childhood, lesions involve flexures, the nape, and the dorsal aspects of the limbs. In adolescence and adulthood, lichenified plaques affect the flexures, head, and neck

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