Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic related skin lesions

addict submitted, created time 1 year 8 months (carcin.oxfordjournals.org)

Single nucleotide polymorphisms in genes related to DNA repair capacity and UV exposure have not been well investigated in relation to skin lesions associated with arsenic exposure. This population based case-control study, of 600 cases and 600 controls, frequency matched on age and gender in Pabna, Bangladesh in 2001-2002, investigated the association and potential effect modification between polymorphisms in XPD (Lys751Gln and Asp312Asn) genes, tendency to sunburn and arsenic related skin lesions

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