Articles with the keyword: 
Sudden hearing loss a harbinger of stroke
kavin submitted, created time 4 months 2 weeks (mobile.reuters.com)
NEW YORK (Reuters Health) - A sudden loss of hearing can be an early warning of impending stroke, according to results of a study released Thursday.
Dr. Herng-Ching Lin and colleagues at Taipei Medical University identified 1423 adult patients hospitalized in 1998 with a first episode of sudden hearing loss and matched each "case" patient to four "control" patients.
Patients in the hearing loss group were significantly more likely to have hypertension (high blood pressure), diabetes, and elevated cholesterol levels, the investigators note 
Bosentan benefits in mild pulmonary arterial hypertension
kavin submitted, created time 4 months 3 weeks (www.thelancet.com)
The EARLY study, published in the June 21, 2008 issue of the Lancet, was conducted by a group led by Dr Nazzareno Galič (University of Bologna, Italy).
They note that bosentan has been shown to improve exercise capacity, hemodynamics, and delay clinical worsening in two pivotal clinical trials, but in these, like other trials of treatments for pulmonary arterial hypertension, the vast majority of enrolled patients were in an advanced symptomatic state (WHO functional class 3 and 4)
Blood Pressure Tougher to Tame in Winter
yangjane submitted, created time 1 year 2 weeks (www.medicinenet.com)
It turns out blood pressure has a chill factor: Hypertension is harder to control in colder weather, heart experts say.
"It has been noted for decades that people's blood pressure tends to be a little bit harder to control or a little bit higher in cold climates," said Dr. Kenneth Baker, M.D., a professor of internal medicine at the Texas A&M Health Science Center College of Medicine.
Isolated Systolic Hypertension in the Elderly
jiangyun submitted, created time 1 year 2 months (content.nejm.org)
A 68-year-old accountant visits his physician. He was told a year earlier that his blood pressure was somewhat elevated and was advised to reduce salt intake and increase physical activity. Otherwise he has been in good health and has no history or signs of cardiovascular or renal disease. On physical examination, his blood pressure is 178/72 mm Hg, with no clinically significant differences between arms or on standing. He has a body-mass index (the weight in kilograms divided by the square of the height in meters) of 28.4. The examination is otherwise unremarkable. Urinalysis is normal
medal submitted, created time 1 year 5 months (hyper.ahajournals.org)
"Inappropriate left ventricular mass predicts the risk of cardiovascular (CV) events, independent of risk factors, either in the presence or in the absence of traditionally defined LV hypertrophy. The relation between changes in appropriateness of LVM during antihypertensive treatment and subsequent prognosis was evaluated in 436 prospectively identified uncomplicated hypertensive subjects, with a baseline and follow-up standard clinical evaluation, laboratory examinations, and echocardiogram (last examination: 6±3 years apart), followed for additional 4.5±2.5 years
Plasma 25-Hydroxyvitamin D Levels and Risk of Incident Hypertension
medal submitted, created time 1 year 5 months (hyper.ahajournals.org)
"Among women, the same comparison yielded a relative risk of 2.67 (95% CI: 1.05 to 6.79). The pooled relative risk combining men and women with measured 25(OH)D levels using the random-effects model was 3.18 (95% CI: 1.39 to 7.29). Using predicted 25(OH)D levels in the larger cohorts, the multivariable relative risks comparing the lowest to highest deciles were 2.31 (95% CI: 2.03 to 2.63) in men and 1.57 (95% CI: 1.44 to 1.72) in women. Plasma 25(OH)D levels are inversely associated with risk of incident hypertension. "
medal submitted, created time 1 year 5 months (hyper.ahajournals.org)
"Insulin resistance syndrome has been observed in women with hypertensive disease of pregnancy, but few studies evaluated the presence of the syndrome a few years after delivery. The objective of this study was to evaluate the presence of insulin resistance and its metabolic alterations in these women compared with those who had a normal pregnancy."
Sodium and Potassium in the Pathogenesis of Hypertension
channel submitted, created time 1 year 6 months (content.nejm.org)
Hypertension affects approximately 25% of the adult population worldwide, and its prevalence is predicted to increase by 60% by 2025, when a total of 1.56 billion people may be affected. It is the major risk factor for cardiovascular disease and is responsible for most deaths worldwide. Primary hypertension, also known as essential or idiopathic hypertension, accounts for as many as 95% of all cases of hypertension.
Barbershops as Hypertension Detection, Referral, and Follow-Up Centers for Black Men
amanda submitted, created time 1 year 6 months (hyper.ahajournals.org)
"Barbershops constitute potential sites for community health promotion programs targeting hypertension (HTN) in black men, but such programs have not been evaluated previously."
Twin Studies Identify Influences of Heredity, Environment, and Adrenergic Pathway Polymorphism
julie submitted, created time 1 year 6 months (hyper.ahajournals.org)
"Albumin excretion marks early glomerular injury in hypertension. This study investigated heritability of albumin excretion in twin pairs and its genetic determination by adrenergic pathway polymorphism. Genetic associations used single nucleotide polymorphisms at adrenergic pathway loci spanning catecholamine biosynthesis, storage, catabolism, receptor action, and postreceptor signal transduction."
julie submitted, created time 1 year 6 months (hyper.ahajournals.org)
"Cigarette smoking is an important modifiable cardiovascular risk factor and pathophysiological mechanisms may include a stiff vascular tree. Although smokers have stiffer arteries, whether smoking cessation is associated with reduced arterial stiffness is not known."
Autosomal Dominant Polycystic Kidney Disease: Time for a Change?
medal submitted, created time 1 year 6 months (jasn.asnjournals.org)
"Diagnosis and treatment of autosomal dominant polycystic kidney disease (ADPKD) is rapidly changing. Cellular pathways that involve the polycystins are being mapped and involve the primary cilium, intracellular calcium and cAMP regulation, and the mammalian target of rapamycin (mTOR) pathway."
Effects of anti-hypertensive drugs on vessel rarefaction
medal submitted, created time 1 year 6 months (www.sciencedirect.com)
"The microcirculation largely determines peripheral vascular resistance and substantially contributes to arterial hypertension. In both human arterial hypertension and animal models of hypertension, genetic, fetal and other mechanisms associated with hypertension can reduce the formation and number of microvessels (i.e. parallel-connected arterioles and capillaries). Impaired formation of microvessels (impaired angiogenesis) and microvascular rarefaction can, on the other hand, contribute to increased peripheral resistance and raise blood pressure. "
Optimal Treatment of Obesity-Related Hypertension
julie submitted, created time 1 year 7 months (circ.ahajournals.org)
"Current guidelines for the treatment of hypertension do not provide specific recommendations for obese hypertensive patients. To identify an optimal treatment regimen for obese hypertensive patients, we studied the interactions between a drug-based weight loss approach by sibutramine and different antihypertensive drug regimens. "
Blame the brain for high blood pressure
alpha submitted, created time 1 year 7 months (www.biologynews.net)
"The controversial idea that one cause of high blood pressure lies within the brain, and not the heart or blood vessels, has been put forward by scientists at the University of Bristol, UK, and is published this week in the journal Hypertension."
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