Articles with the keyword: 
How the Body Determines Optimal Amount of Germ-Fighting B Cells
piggy submitted, created time 1 month 4 weeks (www.sciencedaily.com)
Researchers at the University of Pennsylvania School of Medicine can now explain how the body determines whether there are enough mature B-cells in the blood stream at any one time. These are the cells that produce antibodies against germs to fight infections.
There is a steady state number of B cells that is considered normal for humans, says senior author Michael P. Cancro, PhD, Professor of Pathology and Laboratory Medicine 
Study identifies key player in the body's immune response to chronic stress
sumsung submitted, created time 1 year 4 months (www.eurekalert.org)
Osteopontin, a protein molecule involved in many different cellular processes, plays a significant role in immune deficiency and organ atrophy following chronic physiological stress such as spaceflight, resulting in increased susceptibility to illness.
Regulation of IgA production by naturally occurring TNF/iNOS-producing dendritic cells
jiangyun submitted, created time 1 year 4 months (www.nature.com)
Immunoglobulin-A has an irreplaceable role in the mucosal defence against infectious microbes.This articleshow that IgA class-switch recombination (CSR) is impaired in inducible-nitric-oxide-synthase-deficient (iNOS-/-; gene also called Nos2) mice.
Stabilized immune modulatory RNA compounds as agonists of Toll-like receptors 7 and 8
jiangyun submitted, created time 1 year 4 months (www.pnas.org)
Viral and synthetic single-stranded RNAs are the ligands for Toll-like receptor (TLR)7 and TLR8. However, single-stranded RNA is rapidly degraded by ubiquitous RNases, and the studies reported to date have used RNA with lipid carriers. To overcome nuclease susceptibility of RNA, we have synthesized several RNAs incorporating a range of chemical modifications. The present study describes one pool of RNA compounds, referred to as stabilized immune modulatory RNA (SIMRA) compounds, in which two RNA segments are attached through their 3' ends
Wine-Induced Anaphylaxis and Sensitization to Hymenoptera Venom
jiangyun submitted, created time 1 year 4 months (content.nejm.org)
Alcoholic drinks have been described as triggering or initiating anaphylactoid reactions.Although little is known about the pathogenesis of these reactions,wine contains many biologic and chemical components derived from grapevines, yeast, bacteria, and insects (including those of the order Hymenoptera) that might explain the observed symptoms.
A stepwise retreat: how immune cells catch pathogens
bianjie submitted, created time 1 year 5 months (www.embl.org)
To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalize and destroy them. Using a special microscopy technique, researchers from the European Molecular Biology Laboratory now for the first time tracked the dynamic behavior of these tentacles in three dimensions.
gh0706 submitted, created time 1 year 6 months (bloodjournal.hematologylibrary.org)
Retroviral gene therapy can restore immunity to infants with X-linked severe combined immunodeficiency (XSCID) caused by mutations in the IL2RG gene encoding the common gamma chain (c) of receptors for interleukins 2 (IL-2), 4, 7, 9, 15, and 21. We investigated the safety and efficacy of gene therapy as salvage treatment for older XSCID children with inadequate immune reconstitution despite prior bone marrow transplant from a parent. Subjects received retrovirus-transduced autologous peripherally mobilized CD34+ hematopoietic cells
Immune Molecule Protects Cells Threatened by HIV
catherine submitted, created time 1 year 11 months (www.sciam.com)
Researchers report that a molecule produced by the immune system prolongs the life of immune cells that would normally self-destruct as a result of HIV infection. The finding adds weight to the case for clinical trials to study whether the molecule interleukin-7 (IL-7) when combined with antiretroviral drugs can beef up the immune systems of HIV sufferers.
The researchers observed that IL-7 was more protective of T cells the more advanced the case of HIV was, treatment could be more beneficial for those with advanced infections
Windows submitted, created time 1 year 11 months (www.bioee.com)
Scientists say they have learnt how the body controls the machinery it uses to fight infections and foreign invaders
Immune system fought itself: Study
catherine submitted, created time 1 year 11 months (www.torontosun.com)
The virus that caused the 1918 influenza pandemic triggered an overwhelming immune response that swamped the lungs of macaque monkeys -- the first primates deliberately infected with the Spanish flu virus, Canadian and American scientists reported yesterday.
The research, done in part at the Public Health Agency of Canada's National Microbiology Laboratory in Winnipeg, supports the notion that the virulent flu virus turned the body's immune system against itself. Scientists believe that theory explains how the devastating influenza strain managed to mow down unprecedented numbers of health
humane-wolf submitted, created time 1 year 11 months (www.sciam.com)
Scientists have identified a protein that could help them understand why symptoms of the common cold such as sniffles and congestion last for a limited time.
The previously unknown protein called carabin cranks up the immune system response during an infection and then shuts it off when it has done its job so that it doesn't harm healthy cells.
It?.s an important missing brake within white blood cells that keeps the system in check so it doesn't override itself to cause problems during an virus infection or in the common cold?-..
\ 1
\ 
abuse@discover8.com
angelfish
Darkfrog
jane2007
kavin
Sue Wu
DanyC
addict
amino acid : Fmoc-L-Asp(OtBu)-OH
www.genscript.com
Rat Anti Mouse Thy-1 (CD90) (monoclonal)
CD90 (Thy1) antigen is a GPI linked glycoprotein member of t ...
www.genscript.com
One-StepTM Multiplex Western Kit II (Goat)
Kit : One-StepTM Multiplex Western Kit II (Goat)
www.genscript.com
Rabbit Anti VSV-G-tag (Polyclonal)
This polyclonal rabbit antibody is supplied as a 100 ul aliq ...
www.genscript.com