Articles with the keyword: 
Findings turn events in early TB infection on their head, may lead to new therapy
piggy submitted, created time 7 hours 37 minutes (www.eurekalert.org)
Masses of immune cells that form as a hallmark of tuberculosis (TB) have long been thought to be the body's way of trying to protect itself by literally walling off the bacteria. But a new study in the January 9th issue of the journal Cell, a Cell Press publication, offers evidence that the TB bacteria actually sends signals that encourage the growth of those organized granuloma structures, and for good reason: each granuloma serves as a kind of hub for the infectious bugs in the early stages of infection, allowing them to expand further and spread throughout the body 
piggy submitted, created time 2 days 8 hours (www.sciencedaily.com)
NYU Langone Medical Center scientists and their collaborators at the Scripps Research Institute in La Jolla, California, have discovered an unexpected cause for the fatal seizures seen in mice with viral meningitis, an infection of the central nervous system, according to a study published in the journal Nature. The finding may lead to a new way of thinking about how the human immune system responds to viral diseases.
The NYU researchers, Michael L. Dustin, Ph.D., the Irene Diamond Professor of Immunology and Professor of Pathology at NYU School of Medicine, and Jiyun V. Kim, Ph.D
Inner Workings of the Immune System Filmed
piggy submitted, created time 1 month 3 days (www.sciencedaily.com)
Forget what's number one at the box office this week. The most exciting new film features the intricate workings of the body, filmed by scientists using ground-breaking technology.
For the first time in Australia, scientists at Sydney's Centenary Institute have filmed an immune cell becoming infected by a parasite and followed the infection as it begins to spread throughout the body
Chemical from Medicinal Plants May Be Used to Fight HIV
piggy submitted, created time 1 month 3 weeks (www.sciencedaily.com)
Like other kinds of cells, immune cells lose the ability to divide as they age because a part of their chromosomes known as a telomere becomes progressively shorter with cell division. As a result, the cell changes in many ways, and its disease fighting ability is compromised.
But a new UCLA AIDS Institute study has found that a chemical from the Astragalus root, frequently used in Chinese herbal therapy, can prevent or slow this progressive telomere shortening, which could make it a key weapon in the fight against HIV
Scientists turbo-charge immune cells to fight cancer
piggy submitted, created time 2 months 5 days (news.yahoo.com)
Scientists in the United States have created super-charged immune cells that helped beat back cancer tumors in half of a small group of patients tested, according to a study released Sunday.
Adding an artificial receptor to T-lymphocyte immune cells boosted their ability to fight a deadly form of cancer called neuroblastoma, the researchers reported.
Neuroblastoma attacks the nervous system. While fairly rare, it accounts for seven percent of all childhood cancers, and fifteen percent of non-adult cancer deaths
Good News About Marrow Injections
Sue Wu submitted, created time 11 months 2 weeks (www.reuters.com)
Los Angeles patient Derek Besenfelder, who received a kidney transplant from his mother along with a bone marrow three years ago, has been able to discontinue taking anti-rejections drugs.
Organ transplants without rejection
jane2007 submitted, created time 11 months 2 weeks (www.nature.com)
Three independent research teams have successfully performed organ transplantations that do not require the recipient to face a lifetime of immunosuppressant drugs to prevent rejection. Instead, the new techniques prevent rejection by training the immune system to recognize the new organ as its own.
How Immune Cells Catch Pathogens
broadcast submitted, created time 1 year 5 months (www.medicalnewstoday.com)
To protect us from disease our immune system employs macrophages, cells that roam our body in search of disease-causing bacteria. With the help of long tentacle-like protrusions, macrophages can catch suspicious particles, pull them towards their cell bodies, internalise and destroy them. Using a special microscopy technique, researchers from the European Molecular Biology Laboratory (EMBL) now for the first time tracked the dynamic behaviour of these tentacles in three dimensions
Discovery of an HIV inhibitor in human blood points to new drug class
amanda submitted, created time 1 year 8 months (www.biologynews.net)
"A new study has pinpointed a natural ingredient of human blood that effectively blocks HIV-1, the virus predominantly responsible for human AIDS, from infecting immune cells and multiplying. The virus blocker might play a role in the progression of HIV to full-blown AIDS and—because it works in a different way than existing antiretroviral inhibitors—could lead to the development of another class of drugs in the fight against the pandemic disease, researchers reported in the April 20, 2007 issue of the journal Cell, a publication of Cell Press."
Ikaros and chromatin regulation in early hematopoiesis
athena submitted, created time 1 year 8 months (www.sciencedirect.com)
"Hematopoiesis is the developmental process by which all blood and immune cells are generated. A decade-old scheme has supported an early and complete separation of the erythro-myeloid from the lymphoid lineages. Recent advances have re-drawn this map, separating lymphoid and myeloid from erythroid programs early in development. Subsequently, the fate restriction of both the lympho-myeloid and the erythro-megakaryocyte progenitors is dependent on Ikaros and its associated chromatin regulators
Sandia researchers take new approach to studying how cells respond to pathogens
bioman submitted, created time 1 year 9 months (www.eurekalert.org)
A Sandia National Laboratories research team led by Anup Singh is taking a new approach to studying how immune cells respond to pathogens in the first few minutes and hours of exposure. Their method looks at cells one at a time as they start trying to fight the invading pathogens. Due to the advancement in microfluidics, advanced imaging and Powerful computational modeling.
Gut lymphocyte migration: we are halfway ‘home’
fiona submitted, created time 1 year 9 months (www.sciencedirect.com)
"The gastrointestinal immune system consists of immune cells in organized gut-associated lymphoreticular tissues (GALT) and diffuse lamina propria, which give rise to mucosal secretory IgA antibody responses. A recent study showed that the retinoic acid produced by GALT dendritic cells (DCs) imprints B cells for gut homing. Surprisingly, GALT DCs, together with interleukin-5 (IL-5) and IL-6, also provided a milieu for both B cell switching to IgA and IgA synthesis. "
athena submitted, created time 1 year 9 months (diabetes.diabetesjournals.org)
"Dendritic cells (DCs) are the most potent antigen-presenting cells, yet little data are available on the differential characteristics of donor and recipient DCs (dDCs and rDCs, respectively) during the process of islet allograft rejection. DTR-GFP-DC mice provide a novel tool to monitor DC trafficking and characteristics during allograft rejection."
A Hope for Male Infertility on Stem Cell Research
crackpot submitted, created time 1 year 9 months (health.allrefer.com)
These green cells (fluorescent protein), which could be easily tracked in recipient mice, were injected into the testes of infertile mice, in which infertility was induced either chemically or genetically. The donor stem cells displayed the characteristic shape of either germ cells or supporting cells, suggesting that the stem cells had differentiated. These study data demonstrate that bone marrow stem cells have the potential to differentiate into cells of the testes involved in sperm production, both germ cells and supporting cells
Do you know how common viruses can turn cells cancerous ?
saury submitted, created time 1 year 10 months (www.newscientist.com)
That is named cell fusion - when two or more cells unite by merging membranes - might be to blame. Several common viruses can initiate this process. To test this idea, the researchers took human fibroblast cells with genes that made them more likely to turn into a tumour and infected them with a retrovirus that can cause fusion. Sure enough, fused cells had many more chromosomal abnormalities than unfused ones, and when transplanted into mice, only the fused cells produced tumours .
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