Genetic haplotypes of Th-2 immune signalling link allergy to enhanced protection to parasitic worms

sciencebaby submitted, created time 1 year 7 months (hmg.oxfordjournals.org)

"We investigated how genetic variation in the Th-2 signalling transduction molecule STAT-6 relates to these clinical disorders, using immune phenotyping by serum IgE levels, and haplotyping 9 STAT-6 genetic variants in a rural Chinese population, where Ascaris infection is prevalent, and an urban UK population where Ascaris is largely unknown but asthma and allergy are prevalent. "

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