Articles with the keyword: 


Louse infestation calibrates immune system regulation
piggy submitted, created time 1 year 4 months (www.eurekalert.org)
Some parasites can exert a moderating effect on the immune system, possibly reducing the host's risk of developing immune dysfunctions like asthma, allergies and some forms of arthritis. Researchers writing in the open access journal BMC Biology studied the effects of several parasites on the immune activity of wild wood mice, finding louse infestations to be associated with a reduced readiness to mount an immune response.
Janette Bradley led a team of researchers from the University of Nottingham who carried out the tests on a population of wood mice captured in a Nottinghamshire forest 


New origin found for critical immune response
piggy submitted, created time 1 year 6 months (www.eurekalert.org)
An immune system response critical to the first stages of fighting off viruses and harmful bacteria has been found to come from an entirely different direction than had been thought, say findings from researchers at the Duke University Medical Center.
Type 1 helper (TH1) T cell immune responses are critical for the control of viruses and certain bacteria. Immunologists have generally believed that TH1 responses are induced by rare immune cells, called dendritic cells 


Meningitis bacteria dress up as human cells to evade our immune system
piggy submitted, created time 1 year 6 months (www.eurekalert.org)
The way in which bacteria that cause bacterial meningitis mimic human cells to evade the body's innate immune system has been revealed by researchers at the University of Oxford and Imperial College London.
The study, published in Nature, could lead to the development of new vaccines that give better protection against meningitis B, the strain which accounts for the vast majority of cases of the disease in the UK.
Meningitis involves an inflammation of the membranes covering the brain and the spinal cord as the result of an infection 


How Deadly Fungus Protects Itself
piggy submitted, created time 1 year 6 months (www.sciencedaily.com)
Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how a deadly microbe evades the human immune system and causes disease.
The study, published in the journal Proceedings of the National Academy of Sciences (PNAS), may help scientists develop new therapies or vaccines against infections caused by Cryptococcus neoformans. These fungal infections occur most commonly in those with compromised immune systems ─ especially AIDS patients and transplant patients who must take lifelong immunosuppressive therapy 


Potential New Antibody Treatment for Autoimmune Diseases
piggy submitted, created time 1 year 7 months (www.sciencedaily.com)
Scientists at UCSF have discovered an abnormality in a patient's immune system that may lead to safer therapies for autoimmune diseases such as rheumatoid arthritis and colitis, as well as potential new ways to treat transplant rejection.
The research identified antibodies from a woman’s immune system that prevent infection-fighting T cells from moving through her blood stream and entering her body’s organs to attack invaders such as bacteria or viruses 


DASNR researchers make breakthrough against poxviruses
piggy submitted, created time 1 year 7 months (www2.dasnr.okstate.edu)
Smallpox has a nasty history throughout the world. Caused by poxviruses, smallpox is one of the few disease-causing agents against which the human body’s immune system is ineffective in its defense.
A major breakthrough by Junpeng Deng, a structural biologist in the Division of Agricultural Sciences and Natural Resources (DASNR) at Oklahoma State University, and his first-year Ph.D. student, Brian Krumm, may be the first step towards a pharmaceutical medication for smallpox and the emerging human monkeypox 


Important advance in the treatment of cancer and viral infections
piggy submitted, created time 1 year 7 months (www.eurekalert.org)
Dr. André Veillette, a researcher at the Institut de recherches cliniques de Montréal (IRCM), and his team led by postdoctoral fellow Dr. Mario-Ernesto Cruz-Munoz, will publish in the upcoming issue of the prestigious journal Nature Immunology of Nature Publishing Group. This discovery could have a significant impact on the treatment of cancers and infectious diseases. Current treatments frequently achieve only limited results with these types of diseases, which affect hundreds of thousands of Canadians.
Dr 


piggy submitted, created time 1 year 7 months (www.sciencedaily.com)
NYU Langone Medical Center scientists and their collaborators at the Scripps Research Institute in La Jolla, California, have discovered an unexpected cause for the fatal seizures seen in mice with viral meningitis, an infection of the central nervous system, according to a study published in the journal Nature. The finding may lead to a new way of thinking about how the human immune system responds to viral diseases.
The NYU researchers, Michael L. Dustin, Ph.D., the Irene Diamond Professor of Immunology and Professor of Pathology at NYU School of Medicine, and Jiyun V. Kim, Ph.D 


Antibody fights AIDS-like disease in monkeys
sea-maid submitted, created time 1 year 8 months (www.nature.com)
An antibody treatment has rejuvenated the immune systems of macaques infected with a virus called SIV, allowing the monkeys to fend off the symptoms of an AIDS-like disease for months. SIV is studied as a model for HIV infection in humans, and the therapy could be tested in clinical trials of HIV-infected patients as soon as next year, pending approval by regulators. 


Inner Workings of the Immune System Filmed
piggy submitted, created time 1 year 9 months (www.sciencedaily.com)
Forget what's number one at the box office this week. The most exciting new film features the intricate workings of the body, filmed by scientists using ground-breaking technology.
For the first time in Australia, scientists at Sydney's Centenary Institute have filmed an immune cell becoming infected by a parasite and followed the infection as it begins to spread throughout the body 


Helping the Embryo Implant: A New Role for One Type of Immune Cell
piggy submitted, created time 1 year 9 months (www.sciencedaily.com)
One of the most critical stages in establishing a pregnancy is the implantation of the embryo in the wall of the uterus. Although the accumulation of immune cells known as DCs has been observed in the uterus after fertilization and prior to implantation, their function was not known 


How the Body Determines Optimal Amount of Germ-Fighting B Cells
piggy submitted, created time 1 year 9 months (www.sciencedaily.com)
Researchers at the University of Pennsylvania School of Medicine can now explain how the body determines whether there are enough mature B-cells in the blood stream at any one time. These are the cells that produce antibodies against germs to fight infections.
“There is a steady state number of B cells that is considered normal for humans,” says senior author Michael P. Cancro, PhD, Professor of Pathology and Laboratory Medicine 


New Role for Critical DNA Repair Molecule in Immune System
piggy submitted, created time 1 year 9 months (www.sciencedaily.com)
The human immune system is a brilliantly adaptable weapon against foreign invaders. But it all depends on the work of specialized cells called lymphocytes that have made a risky evolutionary gambit to mutate their own DNA. New research published in Nature shows for the first time that a molecule devoted to DNA repair plays a broader role in this genetic reshuffling — called recombination — than scientists had thought 


Key Gene May Be Crucial to Production of Thymus and Disease-Fighting T-cells
sea-maid submitted, created time 1 year 9 months (gopast.net)
This research provides the first evidence that a key gene may be crucial to maintaining the production of the thymus and its disease-fighting T-cells after an animal’s birth. 


Patient, Heal Thyself: Body's Own Immune Cells Whack Late-Stage Tumor
sea-maid submitted, created time 2 years 2 weeks (www.sciam.com)
In what could be a breakthrough in cancer therapy, researchers report in The New England Journal of Medicine today that they succeeded in bolstering a patient's immune system enough to wipe out late-stage malignant tumors on its own. The scientists say the successful experiment could pave the way for new treatments of advanced cancer that spare patients the side effects of chemotherapy, which kills healthy as well as malignant cells..... 