Articles with the keyword: 
First lipid hormone discovered
jerry submitted, created time 2 weeks 3 days (www.sciencenews.org)
An omega-7 fatty acid made by fat and liver cells acts as a hormone, even mimicking the health benefits of insulin... 
They're calling it "biological alchemy": induced stem cells proliferate
sea-maid submitted, created time 2 months 4 weeks (www.newscientist.com)
CALL it biological alchemy: specialist pancreatic cells that secrete digestive enzymes have been converted directly into insulin-producing beta cells. Meanwhile, epithelial cells from the back of the eye have been coaxed into becoming a versatile, new type of stem cell.
Both advances, reported last week in Philadelphia, Pennsylvania, at the annual meeting of the International Society for Stem Cell Research (ISSCR), may take us closer to a "regenerative" approach to repairing damaged tissue
Novo Nordisk Seeks U.S. and European Approval for Type 2 Drug Liraglutide
kavin submitted, created time 3 months 2 weeks (www.diabeteshealth.com)
Drug manufacturer Novo Nordisk has applied to the U.S. Federal Drug Administration and the European Medicines Agency for approval of liraglutide, a human GLP-1 analog that is taken once daily for the treatment of type 2 diabetes.
The company’s applications are based on a study of 6,500 type 2s, 4,200 of whom received liraglutide as a diet and exercise adjunct. Some of the drug’s recipients used it in combination with other medications used to treat diabetes, while others received it as a monotherapy
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
DanyC submitted, created time 5 months 3 weeks (www.nature.com)
"Here we show that O-GlcNAc transferase (OGT) harbours a previously unrecognized type of phosphoinositide-binding domain. After induction with insulin, phosphatidylinositol 3,4,5-trisphosphate recruits OGT from the nucleus to the plasma membrane, where the enzyme catalyses dynamic modification of the insulin signalling pathway by O-GlcNAc. This results in the alteration in phosphorylation of key signalling molecules and the attenuation of insulin signal transduction."
A Sweet Success for Embryonic Stem Cells
sumsung submitted, created time 7 months 2 weeks (sciencenow.sciencemag.org)
Scientists have for the first time prodded human embryonic stem cells to become functional pancreatic cells. The work, published online today in Nature Biotechnology, marks an important step toward using embryonic stem cells to treat diabetes.
Diabetes study has surprising results
Sue Wu submitted, created time 7 months 3 weeks (www.signonsandiego.com)
The doctors' challenge: explain to 21 million Americans with diabetes how they might be affected by a major study's surprise discovery that lower blood sugar levels are linked to greater numbers of deaths.
Pigs Could Be the Salvation of Diabetes Sufferers
sumsung submitted, created time 8 months 4 days (www.sciam.com)
Most people probably view pigs at best as a source of sustenance or, at worst, as filthy, gluttonous animals. But it seems our porcine pals may also prove invaluable in the fight against type 1 diabetes. Researchers are experimenting with new ways of harvesting insulin-producing islet cells from pigs and transplanting them into diabetes sufferers in the hope of one day reducing the need for daily insulin shots and even replacing them with twice-yearly islet-cell treatments.
Lack of Deep Sleep Raises Diabetes Risk
Sue Wu submitted, created time 9 months 3 days (health.usnews.com)
THURSDAY, Jan. 3 (HealthDay News) -- Failing to sleep deeply for just three nights running has the same negative effect on the body's ability to manage insulin as gaining 20 to 30 pounds, diabetes researchers report.
Eric wu submitted, created time 9 months 1 week (www.sciencenews.org)
In 2000, researchers in Canada reported a possible breakthrough in the treatment of type 1 diabetes. By transfusing insulin-producing cells from donated pancreases into patients, the researchers provided what looked like cures. Within a week after the procedure, all of the first six patients were liberated from daily insulin injections.
Insulin Secretion Aided By Message From Fat Cells
june submitted, created time 10 months 4 weeks (www.medicalnewstoday.com)
In a study using laboratory mice, published in the November 7, 2007 issue of Cell Metabolism, scientists at the School of Medicine report that fat cells release a protein that aids insulin secretion from pancreatic beta cells, which are the sole source of insulin. The protein is an enzyme that the pancreatic cells themselves produce in only minimal amounts. The enzyme works to enhance glucose-stimulated insulin secretion from pancreatic beta cells.
Smart Insulin Nanostructures Pass Feasibility Test, UT Study Reports
benjiamin submitted, created time 1 year 2 weeks (publicaffairs.uth.tmc.edu)
Biomedical engineers at the University of Texas School of Health Information Sciences at Houston have announced pre-clinical test results in the September issue of the International Journal of Nanomedicine demonstrating the feasibility of a smart particle insulin release system that detects spikes in glucose or blood sugar levels and releases insulin to counteract them
MedUnion submitted, created time 1 year 3 weeks (www.mupnet.com)
AIM: This study is to determine if four endogenous growth inhibitors (i.e. four cardiac hormones) can inhibit the activity of extracellular-signal regulated kinases 1/2 (ERK 1/2) stimulated by endogenous growth promoters i.e. insulin and epidermal growth factor (EGF).
METHODS: The phosphorylation of ERK 1/2 was measured with Western blots, while DNA synthesis was measured by bromodeoxyuridine incorporation.
RESULTS: These four peptide hormones, i.e
Sugary drinks, not fruit juice, may be linked to insulin
richard submitted, created time 1 year 1 month (www.eurekalert.org)
Consumption of sugar-sweetened drinks, not including 100 percent fruit juice, may be associated with insulin resistance, even in otherwise healthy adults, according to nutritional epidemiologists at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University in Boston.
Reducing insulin signaling in the brain can prolong lifespan
sumsung submitted, created time 1 year 2 months (www.childrenshospital.org)
A study from Children's Hospital Boston finds that reducing insulin levels in the brain boosts longevity. Though it was done in genetically engineered mice, old-fashioned exercise and good diets also keep brain insulin levels low in humans.
The role of skeletal muscle insulin resistance in the pathogenesis of the metabolic syndrome
sumsung submitted, created time 1 year 2 months (www.pnas.org)
We examined the hypothesis that insulin resistance in skeletal muscle promotes the development of atherogenic dyslipidemia, associated with the metabolic syndrome, by altering the distribution pattern of postprandial energy storage.
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