Articles with the keyword: 
Virus said to trigger childhood-onset diabetes
sea-maid submitted, created time 1 year 1 week (news.bbc.co.uk)
U.K. researchers report that enteroviruses may be triggers for type I diabetes, particularly in children. In a study of diabetic children, pancreatic tissue from 60% of the subjects was shown to be infected with enterovirus. Hardly any non-diabetic children showed any enterovirus at all. In adults this figure was closer to 40%.
Type I diabetes is an autoimmune disease in which the body kills off its own beta cells (this is as opposed to type II diabetes, in which the body's insulin receptors are damaged or less sensitive) 
On a High-Fat Diet, Protective Gene Variant Becomes Bad Actor
sea-maid submitted, created time 1 year 2 months (www.sciencedaily.com)
New evidence in mice bolsters the notion that a version of a gene earlier shown to protect lean people against weight gain and insulin resistance can have the opposite effect in those who eat a high-fat diet and are heavier, reveals a report in the January 7th issue of the journal Cell Metabolism, a Cell Press publication
Hope of insulin cell transplant
sea-maid submitted, created time 1 year 2 months (news.bbc.co.uk)
Scientists working towards pancreatic cell transplants as a cure for diabetes have taken the first step to getting around the problem of immune rejection.
piggy submitted, created time 1 year 3 months (sciencenow.sciencemag.org)
Is there a link between sleep and type 2 diabetes? That's one implication of a new study, which has found that variants in a gene that helps regulate the body's daily rhythms increase the chance of developing the disease. The find, reported online yesterday in three papers in Nature Genetics, may suggest new ways to treat or prevent the ever more common disorder.
The body's internal clock--which controls the circadian rhythm--is kept accurate by a hormone called melatonin, whose levels fall during the day and rise at night
Pure Insulin-Producing Cells Produced in Mice
piggy submitted, created time 1 year 4 months (www.sciencedaily.com)
Singapore researchers have developed an unlimited number of pure insulin-producing cells from mouse embryonic stem cells (ESCs).
These pure insulin-producing cells, which according to electron microscopy studies, have the same sub-cellular structures as the insulin-producing cells naturally found in the pancreas, were highly effective in treating diabetes in the mouse model.
The transplants of pure insulin-producing cells reduced the blood glucose levels of diabetic mice with high blood glucose levels
GlaxoSmithKline's customized "red wine" drug potent in mice
piggy submitted, created time 1 year 4 months (www.reuters.com)
LONDON (Reuters) - A drug in development that mimics a health-boosting compound found in red wine may be a powerful weapon in the fight against obesity and diabetes, researchers said on Tuesday.
A study of mice showed that the GlaxoSmithKline drug SRT1720 was about a thousand times more potent than resveratrol in activating an enzyme that helped the animals burn more energy and lower their insulin and glucose levels
First lipid hormone discovered
jerry submitted, created time 1 year 6 months (www.sciencenews.org)
An omega-7 fatty acid made by fat and liver cells acts as a hormone, even mimicking the health benefits of insulin...
They're calling it "biological alchemy": induced stem cells proliferate
sea-maid submitted, created time 1 year 8 months (www.newscientist.com)
CALL it biological alchemy: specialist pancreatic cells that secrete digestive enzymes have been converted directly into insulin-producing beta cells. Meanwhile, epithelial cells from the back of the eye have been coaxed into becoming a versatile, new type of stem cell.
Both advances, reported last week in Philadelphia, Pennsylvania, at the annual meeting of the International Society for Stem Cell Research (ISSCR), may take us closer to a "regenerative" approach to repairing damaged tissue
Novo Nordisk Seeks U.S. and European Approval for Type 2 Drug Liraglutide
kavin submitted, created time 1 year 9 months (www.diabeteshealth.com)
Drug manufacturer Novo Nordisk has applied to the U.S. Federal Drug Administration and the European Medicines Agency for approval of liraglutide, a human GLP-1 analog that is taken once daily for the treatment of type 2 diabetes.
The company’s applications are based on a study of 6,500 type 2s, 4,200 of whom received liraglutide as a diet and exercise adjunct. Some of the drug’s recipients used it in combination with other medications used to treat diabetes, while others received it as a monotherapy
Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance
DanyC submitted, created time 1 year 11 months (www.nature.com)
"Here we show that O-GlcNAc transferase (OGT) harbours a previously unrecognized type of phosphoinositide-binding domain. After induction with insulin, phosphatidylinositol 3,4,5-trisphosphate recruits OGT from the nucleus to the plasma membrane, where the enzyme catalyses dynamic modification of the insulin signalling pathway by O-GlcNAc. This results in the alteration in phosphorylation of key signalling molecules and the attenuation of insulin signal transduction."
A Sweet Success for Embryonic Stem Cells
sumsung submitted, created time 2 years 1 month (sciencenow.sciencemag.org)
Scientists have for the first time prodded human embryonic stem cells to become functional pancreatic cells. The work, published online today in Nature Biotechnology, marks an important step toward using embryonic stem cells to treat diabetes.
Diabetes study has surprising results
Sue Wu submitted, created time 2 years 1 month (www.signonsandiego.com)
The doctors' challenge: explain to 21 million Americans with diabetes how they might be affected by a major study's surprise discovery that lower blood sugar levels are linked to greater numbers of deaths.
Pigs Could Be the Salvation of Diabetes Sufferers
sumsung submitted, created time 2 years 1 month (www.sciam.com)
Most people probably view pigs at best as a source of sustenance or, at worst, as filthy, gluttonous animals. But it seems our porcine pals may also prove invaluable in the fight against type 1 diabetes. Researchers are experimenting with new ways of harvesting insulin-producing islet cells from pigs and transplanting them into diabetes sufferers in the hope of one day reducing the need for daily insulin shots and even replacing them with twice-yearly islet-cell treatments.
Lack of Deep Sleep Raises Diabetes Risk
Sue Wu submitted, created time 2 years 2 months (health.usnews.com)
THURSDAY, Jan. 3 (HealthDay News) -- Failing to sleep deeply for just three nights running has the same negative effect on the body's ability to manage insulin as gaining 20 to 30 pounds, diabetes researchers report.
Eric wu submitted, created time 2 years 2 months (www.sciencenews.org)
In 2000, researchers in Canada reported a possible breakthrough in the treatment of type 1 diabetes. By transfusing insulin-producing cells from donated pancreases into patients, the researchers provided what looked like cures. Within a week after the procedure, all of the first six patients were liberated from daily insulin injections.
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