Distinct roles of E2F proteins in vascular smooth muscle cell proliferation and intimal hyperplasia

bianjie submitted, created time 1 year 5 months (www.pnas.org)

Intimal hyperplasia (IH) and restenosis limit the long-term utility of bypass surgery and angioplasty due to pathological proliferation and migration of vascular smooth muscle cells (VSMCs) into the intima of treated vessels.

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