Articles with the keyword:
10

At Risk for Kidney Disease? Check Your Genes

sea-maid submitted, created time 11 months 8 hours (www.sciencedaily.com)

Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease (CKD), according to a new study. The results may be important for determining patients' health risks and for devising new medical treatments.

10

Drug Combination Reduces Risk of Kidney Disease in Diabetics

sea-maid submitted, created time 1 year 2 weeks (www.sciencedaily.com)

For patients with type two diabetes, a combination of two blood-pressure-lowering drugs reduces the risk of kidney disease by about twenty percent—even in patients who don't have high blood pressure, reports a study in the April 2009 issue of the Journal of the American Society of Nephrology (JASN).

10

Gene Mutation Increases Drug Toxicity, Rejection Risk in Pediatric Kidney Transplants

sea-maid submitted, created time 1 year 3 weeks (www.sciencedaily.com)

Screening for mutations in a gene that helps the body metabolize a kidney transplant anti-rejection drug may predict which children are at higher risk for side effects, including compromised white blood cell count or organ rejection, according to new research.

12

Impaired Kidney Function Raises Risk of Heart Problems in the Elderly

sea-maid submitted, created time 1 year 1 month (www.sciencedaily.com)

A study published in the open access journal PLoS Medicine suggests that elderly people with damaged kidneys are at greater risk of cardiovascular disease, such as heart failure and stroke, and other causes of mortality. The findings indicate that greater efforts should be made to encourage elderly people who have impaired kidney function alongside other risk factors—such as high blood cholesterol and high blood pressure, which are often a result of smoking and diet—to make lifestyle changes to avoid developing cardiovascular problems.

8

Singapore to examine kidney trading

sea-maid submitted, created time 1 year 7 months (news.yahoo.com)

Singapore is considering legalizing kidney trading to help meet demand for kidney transplants, the city-state's health minister said Monday

10

Development of end stage renal disease following an acute cardiac event

sea-maid submitted, created time 1 year 8 months (www.nature.com)

The author determined the rate and risk factors for end-stage renal disease (ESRD) in consecutive patients discharged after a cardiac event in a large, unbiased Canadian cohort that receives universal health coverage.

7

RhoA/Rho-Kinase Contribute to the Pathogenesis of Diabetic Renal Disease

jerry submitted, created time 1 year 9 months (diabetes.diabetesjournals.org)

This article tells us that high glucose activates RhoA/Rho-kinase in MCs, leading to downstream AP-1 activation and fibronectin induction. Inhibition of this pathway in vivo prevents the pathologic changes of diabetic nephropathy, supporting a potential role for inhibitors of RhoA/Rho in the treatment of diabetic renal disease.

6

New Combo Treatment Extends Kidney Cancer Survival

asuser submitted, created time 2 years 2 months (health.allrefer.com)

A combination treatment with two drugs, Avastin (bevacizumab) plus interferon, extends the life of patients with kidney cancer, European researchers report.

5

CD4(+) T-cell recognition of human 5T4 oncofoetal antigen: implications for initial depletion of CD25(+) T cells

Immunology submitted, created time 2 years 3 months (www.ncbi.nlm.nih.gov)

BACKGROUND: The human 5T4 (h5T4) oncofoetal antigen is expressed by a wide variety of human carcinomas including colorectal, ovarian, gastric and renal, but rarely on normal tissues. Its restricted expression on tumour tissues as well as its association with tumour progression and bad prognosis has driven the development of a MVA-based vaccine (TroVax) which has been tested in several early phase clinical trials and these studies have led to the start of a phase III trial in renal cell carcinoma patients

7

Insomnia may lead to toilet visits

merry submitted, created time 2 years 7 months (www.reutershealth.com)

Tests on 20 people who were deliberately deprived of sleep produced more urine at night, and it was saltier than usual, the researchers said. The effects were much stronger in men than in women.

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