Cardiac manifestations of Anderson–Fabry disease: results from the international Fabry outcome survey

fiona submitted, created time 1 year 7 months (eurheartj.oxfordjournals.org)

"This study confirms the high prevalence of cardiac morbidity associated with AFD. The disease burden in treated women exceeds that of untreated men, suggesting that most women selected for ERT have advanced disease. The presence of LVH is associated with higher frequency of cardiac signs and symptoms and relates independently to gender, age, and renal function. "

Submit comment | Blog It | Email It | Keywords: Anderson–Fabry disease Cardiomyopathy Left ventricular hypertrophy Lysosomal storage disease Agalsidase alfa

Genetic Variations Associated With Echocardiographic Left Ventricular Traits in Hypertensive Blacks

julie submitted, created time 1 year 8 months (hyper.ahajournals.org)

"Echocardiographic measures of cardiac target organ damage, including left ventricular mass and relative wall thickness, are powerful predictors of heart disease morbidity and mortality."

Submit comment | Blog It | Email It | Keywords: single nucleotide polymorphism association echocardiography left ventricular hypertrophy ventricular remodeling

Ambulatory Arterial Stiffness Index Is Not a Specific Marker of Reduced Arterial Compliance

julie submitted, created time 1 year 8 months (hyper.ahajournals.org)

"Ambulatory arterial stiffness index (AASI), a measure based on the relative behavior of 24-hour systolic and diastolic blood pressure (BP), has been suggested as a marker of arterial stiffness and a predictor of cardiovascular mortality."

Submit comment | Blog It | Email It | Keywords: ambulatory blood pressure monitoring arteries blood pressure arterial stiffness left ventricular hypertrophy

Corin I555(P568) Allele Is Associated With Enhanced Cardiac Hypertrophic Response to Increased Systemic Afterload

julie submitted, created time 1 year 8 months (hyper.ahajournals.org)

"Corin activates pro–A-type naturetic peptide and pro–B-type naturetic peptide into biologically active molecules."

Submit comment | Blog It | Email It | Keywords: hypertension left ventricular hypertrophy natriuretic peptides genetic polymorphisms left ventricular remodeling