Articles with the keyword: 
Smoking and solid fuel use in homes cause millions of deaths
sea-maid submitted, created time 1 day 20 hours (esciencenews.com)
If current levels of smoking and biomass and coal fuel use in homes continues, between 2003 and 2033 there will be an estimated 65 million deaths from chronic obstructive pulmonary disease (COPD) and 18 million deaths from lung cancer in China, accounting for 19% and 5% of all deaths in that country during this period. Researchers at the Harvard School of Public Health (HSPH) predict that the combined effects of these two major factors alone will be responsible for more than 80% of COPD deaths and 75% of lung cancer deaths in China over a thirty-year period 
Burning incense linked to respiratory cancers
sea-maid submitted, created time 1 month 1 week (www.reuters.com)
Burning incense may create a sweet scent, but regularly inhaling the smoke could put people at risk of cancers of the respiratory tract, researchers reported Monday.
Lung cancer screening: the way forward
sea-maid submitted, created time 1 month 2 weeks (www.nature.com)
To take lung cancer screening into national programs, we first have to answer the question whether low-dose computed tomography (LDCT) screening and treatment of early lesions will decrease lung cancer mortality compared with a control group, to accurately estimate the balance of benefits and harms, and to determine the cost-effectiveness of the intervention.
Experimental chemotherapy regimen shows promise in treating advanced lung cancer
sea-maid submitted, created time 1 month 3 weeks (www.eurekalert.org)
A combination of chemotherapy agents that have been tested in other tumor types appears to be a promising alternative to standard treatment for advanced nonsmall cell lung cancer, according to a report in the Aug. 15 issue of Clinical Cancer Research, a journal of the American Association for Cancer Research.
Faulty DNA repair could be a risk factor for lung cancer in nonsmokers
sea-maid submitted, created time 3 months 1 week (esciencenews.com)
People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability, according to researchers from the Department of Epidemiology at The University of Texas M. D. Anderson Cancer Center. "About 15 percent of lung cancers occur in lifetime never smokers
jerry submitted, created time 4 months 2 weeks (jco.ascopubs.org)
This study tells us that both clinical patient characteristics and molecular tumor markers may be used to predict the likelihood of response to EGFR TKI therapy.
It is likely—indeed probably inevitable—that a panel of tests will be used in the not too distant future to determine which patients are likely to respond, and of almost equal importance, to determine which patients are unlikely to derive benefit from EGFR inhibitor therapy
Cell: A key pathway of acute lung injury-Oxidative
kavin submitted, created time 5 months 2 weeks (www.cell.com)
Multiple lung pathogens such as SARS cause high lethality due to acute respiratory distress syndrome. The researchers, through experiments in mice, indentify oxidative stress and innate immunity as key lung injury pathways that control the severity of ALI.
Why Some Smokers Get Lung Cancer--And Others Are Spared
sumsung submitted, created time 5 months 3 weeks (www.sciam.com)
Smoking is the most potent known cause of lung cancer. The question is: Why do some longtime smokers come down with the deadly disease whereas others escape it? New research points to a genetic culprit that also was fingered as upping a person's likelihood of becoming hooked on cigarettes.
First Common Genetic Clue to Lung Cancer
sumsung submitted, created time 6 months 4 days (sciencenow.sciencemag.org)
It's well known that cigarettes can cause lung cancer. A nd yet, some people smoke like a chimney their entire lives and never get the disease. Now a sweeping search for an explanation has yielded a clue: Three studies have found a marker in the same region of DNA that appears to raise the risk of lung cancer. But the researchers disagree on whether the gene involved directly causes lung cancer or does so by influencing how easily people get hooked on tobacco.
jane2007 submitted, created time 6 months 4 days (www.nature.com)
There are many smokers thought out the world, so why do some of them delevop lung cancer? Why not others? A new study suggests that, amongst smokers, some people may be as much as 80% more at risk than others thanks to their genes.
Vitamin E Supplements Linked to Lung Cancer
Sue Wu submitted, created time 7 months 3 days (medheadlines.com)
According to a study published in the March issue of the American Thoracic Society’s American Journal of Respiratory and Critical Care Medicine, vitamin E can increase the risk of developing lung cancer.
High-resolution mapping of DNA hypermethylation and hypomethylation in lung cancer
davidd submitted, created time 8 months 4 weeks (www.pnas.org)
Changes in DNA methylation patterns are an important characteristic of human cancer. Here, they used high-resolution genotyping and CpG island arrays to analyze methylation patterns in lung squamous cell carcinomas and matched normal lung tissue. Normal tissues from different individuals showed overall very similar DNA methylation patterns. Each tumor contained several hundred hypermethylated CpG islands. We identified and confirmed 11 CpG islands that were methylated in 80–100% of the SCC tumors, and many hold promise as effective biomarkers for early detection of lung cancer.
jane2007 submitted, created time 10 months 2 days (www.nature.com)
In 1981, Nature published a review about the possible link between high levels of dietary β-carotene and reduced rates of cancer.
In 1994, the results of those trials were in: β-carotene supplements, given together with vitamin E, did not protect against lung cancer as epidemiological studies had suggested they might. Instead, the supplements may actually have raised risk of developing the disease for male smokers.
Gene chip helps doctor target cancer treatment
DanyC submitted, created time 1 year 2 weeks (www.reutershealth.com)
It looked bad for Chuck Fleming -- lung cancer had spread through his body. But his oncologist decided to try using a "gene chip" to see which out of a laundry list of chemotherapy options might work best
Lung cancer screening ruled out
Paradise submitted, created time 1 year 3 weeks (www.newscientist.com)
Lung cancer screening does not necessarily provide any benefit to patients and might actually cause unnecessary harm, says the organisation in its updated set of lung-cancer guidelines published on Monday.
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