Articles with the keyword:
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Brain Reorganizes to Adjust for Loss of Vision

piggy submitted, created time 21 hours 5 minutes (www.sciencedaily.com)

A new study from Georgia Tech shows that when patients with macular degeneration focus on using another part of their retina to compensate for their loss of central vision, their brain seems to compensate by reorganizing its neural connections. Age–related macular degeneration is the leading cause of blindness in the elderly. The study appears in the December edition of the journal Restorative Neurology and Neuroscience

7

Discovery of natural compounds that could slow blood vessel growth

sea-maid submitted, created time 1 month 2 weeks (esciencenews.com)

Using a whole-genome approach, researchers have found more than one hundred human protein compounds that can slow blood vessel growth. This could lead to treatments against diseases that depend on the growth of new blood vessels, including cancer, macular degeneration and rheumatoid arthritis.

8

Retinal transplants bear threefold fruit

Darkfrog submitted, created time 2 months 1 week (www.nature.com)

A formerly clinically blind woman's vision improved from 20/800 to 20/160--from one-fortieth of ordinary vision to one-eighth--after receiving donated retina. Six months after the operation, the started noticing the pendulum in her grandfather clock. For years, she found that she could read large-print books and emails and returned to her hobbies, knitting and sewing. Now, six years after her operation, her vision is fading, but it is still better than it was before the operation

5

Experimental RNA drug may cause blindness

lavrock submitted, created time 2 months 3 weeks (www.nature.com)

Caution needed in clinical trials, scientists urge.

12

Algal protein causes blind mice to react to light

Darkfrog submitted, created time 6 months 3 weeks (www.nature.com)

Blind mice have been made to react to light in the lab. Scientists have used a protein found in algae to make little systems that react to light. When properly attached, these proteins can switch neurons on and off almost like natural photoreceptors do. It's not too clear how well the mice can actually see, but they can now tell the difference between "lights on" and "lights off." The scientists suppose, too, that the mice can only see in black and white

8

Triumphs and tribulations for RNA interference

jane2007 submitted, created time 7 months 3 weeks (www.nature.com)

Two studies highlight promise and problems for gene silencing technique. Researchers could offer a new way by microRNA interference to treat conditions from cancer to cardiovascular disease. But another study shows that the effects of RNAi on genes involved in a severe form of blindness called age-related macular degeneration (AMD). In this case RNAi-causing drugs have already gone into trials. It isn't that the drugs don't work; it's that they work no matter what siRNA sequence is used. This brings the current understanding of the mechanism of RNA interference into question.

7

A gene related to one of the leading causes of blindness has been found

DanyC submitted, created time 8 months 3 days (www.efluxmedia.com)

New research reveals that a gene called Robo4 could help curb or prevent two leading causes of blindness: age-related macular degeneration (AMD) and diabetic retinopathy. The Robo4 gene not only stopped the uncontrolled growth of the weak and leaky eye vessels, it also reversed the vessel damage. Dr. Li said clinical trials on human would probably take place within the next 5 year.

AMD:the American Academy of Ophthalmology

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