Articles with the keyword:
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Potential Therapeutic Strategy for Type I Diabetes

jerry submitted, created time 3 months 3 days (diabetes.diabetesjournals.org)

Mesenchymal stem cells (MSCs) are pluripotent stromal cells that have the potential to give rise to cells of diverse lineages. Interestingly, MSCs can be found in virtually all postnatal tissues. The main criteria currently used to characterize and identify these cells are the capacity for self-renewal and differentiation into tissues of mesodermal origin, combined with a lack in expression of certain hematopoietic molecules. Because of their developmental plasticity, the notion of MSC-based therapeutic intervention has become an emerging strategy for the replacement of injured tissues

6

Stem cell genes may provide medicine's dream ticket

Reviver submitted, created time 1 year 3 months (www.newscientist.com)

"GENE therapy meets stem cells. That is the wave of the future, if the recent annual meeting of the American Society of Gene Therapy in Seattle is any guide. There was a palpable buzz around efforts to correct diseases by targeting therapeutic genes to stem cells already resident in the body.Stem cells have obvious appeal as targets for gene therapy, in which genes are inserted into an individual's cells in order to treat a disease

5

Stem cell eye repair discovery

crackpot submitted, created time 1 year 4 months (www.news.com.au)

STEM cells made from human embryos can home in on damaged eyes, hearts and arteries of mice and rats, and appear to start repairs, a US company says. Massachusetts-based Advanced Cell Technology said it had devised a straightforward way to make blood vessel precursor cells out of the stem cells and plans to test them in humans.

6

The osteogenicity of implanted engineered bone constructs is related to the density of clonogenic bone marrow stromal cells

BIOBOSS submitted, created time 1 year 5 months (www3.interscience.wiley.com)

Reproducible osteogenicity is a key requirement for the clinical use of bone substitutes based on bone marrow stromal cells (BMSCs) and three-dimensional (3D) scaffolds. In this study we addressed whether a minimal cell density is required for ectopic osteogenicity of constructs generated using a recently developed perfusion system for seeding and culturing human BMSCs on 3D scaffolds.

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