MedUnion submitted, created time 10 months 3 weeks (www.mupnet.com)

AIM: EpCAM (CD326) is a transmembrane glycoprotein on epithelial cells. To assess its expression, an increasing number of commercially available antibodies combined with multiple staining protocols with varying sensitivities and specificities are in use. There is no consensus about definition of positivity. Systematic and reliable comparison of results is therefore hampered. To maximise the reproducibility of the results, we investigated EpCAM expression on tissue microarrays

Submit comment | Blog It | Email It | Keywords: carcinoids microarrays adenocarcinomas cancer squamous cell carcinoma tissue microarrays EpCAM

Eric wu submitted, created time 11 months 3 weeks (www.sciencedaily.com)

Scientists at Arizona State University's Biodesign Institute have developed the world's first gene detection platform made up entirely from self-assembled DNA nanostructures. The results, appearing in the January 11 issue of the journal Science, could have broad implications for gene chip technology and may also revolutionize the way in which gene expression is analyzed in a single cell.

Submit comment | Blog It | Email It | Keywords: gene chips gene expression profile nanotechnology gene detection microarrays gene-delivery technology