Cutting the cord--mitosis and separation

sea-maid submitted, created time 7 months 2 weeks (www.jcb.org)

From this resport, we know that like parents sending their child off to college, a dividing cell has to let its offspring go. A microtubule-organizing protein helps ensure that the daughter cell breaks free.

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Vik1 Modulates Microtubule-Kar3 Interactions through a Motor Domain that Lacks an Active Site

claudia submitted, created time 1 year 9 months (www.cell.com)

Conventional kinesin and class V and VI myosins coordinate the mechanochemical cycles of their motor domains for processive movement of cargo along microtubules or actin filaments. It is widely accepted that this coordination is achieved by allosteric communication or mechanical strain between the motor domains, which controls the nucleotide state and interaction with microtubules or actin. However, questions remain about the interplay between the strain and the nucleotide state

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