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8

The Iceman's mysterious genetic past

sea-maid submitted, created time 1 month 1 day (www.sciencenews.org)

A 5,000-year-old mummy displays a genetic signature no longer found in Europe, according to its complete mitochondrial DNA sequence.

8

Caveman's DNA Looks Modern

jerry submitted, created time 4 months 1 week (sciencenow.sciencemag.org)

When it comes to the extremely difficult task of sequencing caveman DNA, the third time may be the charm for David Caramelli. After two controversial attempts, the biological anthropologist at the University of Florence, Italy, and colleagues claim to have successfully sequenced mitochondrial DNA (mtDNA) from the fossils of a Cro-Magnon, a 28,000-year-old European ancestor of living humans. The mtDNA matches that of some modern Europeans but differs from that of Neandertals, shedding light on the fate of these ancient hominids

8

Mitochondrial Mutations Make Tumors Spread

jane2007 submitted, created time 7 months 3 weeks (sciencenow.sciencemag.org)

Why is it that cancer often strikes its final, fatal blow when a tumor spreads to other organs? It's because of the metastasis of mitochondrial DNA mutations.

10

Fossil faces pinpoint earliest North Americans

jane2007 submitted, created time 7 months 4 weeks (www.nature.com)

Some 14,300-year-old fossilized human feces have been found in Oregon, offering the oldest firm evidence yet of humans in North America, and the oldest human DNA in all the Americas.

8

Further review of "three-parent" embryo technique

Darkfrog submitted, created time 9 months 3 weeks (www.nature.com)

This is another discussion of the mother-father-mitochondiadonor embryo that I mentioned the other day. It is significantly more revealing. It seems that the mitochondrial transfer involved moving nuclear DNA from the diseased embryo to the healthy one instead of into an ovum from another source.

It also discusses their methods. It seems that the exchange was performed in embryos that had failed in other experiments. The ten successes came from many failures. The specific success to failure ratio is not given.

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