Long-Term Benefits of Morphine Treatment in Infants Confirmed in Rodent Study

sea-maid submitted, created time 2 months 2 days (www.filterproof.com)

A recent study conducted by researchers at Georgia State University is the first of its kind to demonstrate that administration of preemptive morphine prior to a painful procedure in infancy blocks the long-term negative consequences of pain in adult rodents. These studies have serious implications for the way anesthetics and analgesics are administered to neonates prior to surgery.

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Ovulation-blocking gene found

Mice ascend Everest to combat doping in sport

jerry submitted, created time 7 months 1 week (www.newscientist.com)

Researchers are looking for biochemical markers of the body's response to high altitude, as they could provide a test for gene doping by athletes...

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Algal protein causes blind mice to react to light

Darkfrog submitted, created time 8 months 1 week (www.nature.com)

Blind mice have been made to react to light in the lab. Scientists have used a protein found in algae to make little systems that react to light. When properly attached, these proteins can switch neurons on and off almost like natural photoreceptors do. It's not too clear how well the mice can actually see, but they can now tell the difference between "lights on" and "lights off." The scientists suppose, too, that the mice can only see in black and white

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A research about stem cell

sea-maid submitted, created time 8 months 2 weeks (www.jcb.org)

This article stated an experiment which used a mouse mold of HGPS to tell us the relationship between the stem cell and the disease that resembles preamature-aging. These findings establish a link between age-related nuclear envelope defects and stem cell dysfunction.

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Mouse model could provide clues to autistic behaviors

jane2007 submitted, created time 9 months 3 weeks (news-service.stanford.edu)

A study focused on mice missing the gabrb3 gene have developed a new mouse model to help illuminate the vagaries of autism.

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Sniffling mice raise therapy hope

Sue Wu submitted, created time 11 months 3 days (24hnews.net)

Scientists have created a mouse that can catch a cold - raising hopes of new ways to treat serious respiratory conditions and asthma.

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'Painkiller' gene turned off in mice

Eric wu submitted, created time 1 year 2 weeks (www.newscientist.com)

Mice lacking a key protein took longer to react to a painful stimulus, prompting hopes for a new class of painkillers

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Reduced cortical inhibition in a mouse model of familial childhood absence epilepsy

kitty submitted, created time 1 year 2 months (www.pnas.org)

Mutations in the GABAA receptor γ2 subunit are associated with childhood absence epilepsy and febrile seizures. To understand better the molecular basis of absence epilepsy in man, we developed a mouse model harboring a γ2 subunit point mutation (R43Q) found in a large Australian family. Mice heterozygous for the mutation demonstrated behavioral arrest associated with 6-to 7-Hz spike-and-wave discharges, which are blocked by ethosuximide, a first-line treatment for absence epilepsy in man.

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A mouse model for nonsense mutation bypass therapy shows a dramatic multiday response to geneticin

brooke submitted, created time 1 year 3 months (www.pnas.org)

Aminoglycosides can bypass nonsense mutations and are the prototypic agents for translational bypass therapy (TBT). Initial results demonstrate the need for more potent drugs and an in vivo model system for quantitative assessment of TBT.

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Body Clock Disruption Brings on Manic Behavior

athena submitted, created time 1 year 9 months (www.sciam.com)

"In the past, when researchers sought clues in mouse models for insomnia, hyperactivity, irresponsible risk-taking, drug abuse and other behavior associated with mania, they shot up the animals with amphetamines and monitored their actions. But those experiments yielded only limited information. "

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A mouse model of basal-like breast carcinoma with metaplastic elements

BIOBOSS submitted, created time 1 year 9 months (www3.interscience.wiley.com)

Researchers in the Breakthrough Breast Cancer Research Centre have generated a mouse model of basal-like breast cancer, which should prove useful in testing new and targeted treatments for this type of breast cancer.

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