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13

New Family of Antibacterial Agents Uncovered

sea-maid submitted, created time 1 year 7 months (www.sciencedaily.com)

As bacteria resistant to commonly used antibiotics continue to increase in number, scientists keep searching for new sources of drugs. One potential new bactericide has now been found in the tiny freshwater animal Hydra.

10

Antibacterial drugs: New paths to beating bacteria

sea-maid submitted, created time 1 year 10 months (www.nature.com)

The need for new drugs to combat multidrug-resistant bacteria remains pressing. Now, two recent papers published in Science describe novel agents that target different mechanisms to currently approved antibacterials, which may help tackle this challenge.

The first study, by Haydon and colleagues, set out to target bacterial cell division. FtsZ is an essential bacterial protein that undergoes GTP-dependent polymerization to form the Z ring — the site of cell division — promoting the sequential recruitment of additional proteins that are vital to the process

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