Articles with the keyword: 
A better understanding of inherited breast cancer
sea-maid submitted, created time 1 month 1 day (www.sciencenews.org)
One of the molecular players in breast cancer arising from an inherited mutation has a surprising role in squelching tumors. 
sea-maid submitted, created time 2 months 1 day (www.sciencenews.org)
Men who father children with multiple women are responsible for “extra” diversity on the X chromosome, a new study of six different populations suggests.
FDA Approves First Drug for Treatment of Chorea in Huntington’s Disease
kavin submitted, created time 3 months 2 weeks (www.fda.gov)
The U.S. Food and Drug Administration has approved Xenazine (tetrabenazine) for the treatment of chorea in people with Huntington’s disease. Chorea is the jerky, involuntary movement that occurs in people with this disease.
Xenazine is a new drug and is the first treatment of any kind approved in the United States for any symptom of Huntington’s disease. Currently there are no other drugs that are FDA-approved to treat chorea.
Serious side effects reported with use of Xenazine include depression and suicidal thoughts and actions
Evolution and historical continguency caught on tape! E. coli amass traits over time.
Darkfrog submitted, created time 5 months 2 weeks (www.pnas.org)
Historical contingency is a new phrase for me. I gather that it means "the idea that a given new mutation cannot create a new trait unless certain other, related mutations have already taken place." Anyway, it's been observed, repeatedly, in a laboratory setting.
Researchers split some identical E. coli into twelve colonies and gave them a glucose-poor medium that contained citrate, which E. coli cannot ordinarily process. Eventaully, around generation 32,000 some of the E. coli gained the ability to use citrate as food
Mutation Spells Bad News for Breast Cancer Patients
sea-maid submitted, created time 6 months 1 day (sciencenow.sciencemag.org)
Breast cancer patients with a mutation in both copies of the NQO1 gene have a 20% lower survival rate five years after treatment than do patients without the mutation, according to a new study of more than 2000 Finnish women.
Ozone layer would be damaged by limited nuclear war
sea-maid submitted, created time 6 months 2 weeks (environment.newscientist.com)
This study points out that even a small-scale nuclear war between, say, India and Pakistan would destroy much of the ozone layer, leaving the DNA of humans and other organisms at risk of damage from the sun's rays and increasing the risk of skin cancer worldwide.
Mutation May Explain Deadly Form of Leukemia
Sue Wu submitted, created time 7 months 2 weeks (sciencenow.sciencemag.org)
A new study indicates that mutations in the Ikaros gene play a role in triggering acute lymphoblastic leukemia (ALL), an aggressive, treatment-resistant form of cancer.
Why Some Smokers Get Lung Cancer--And Others Are Spared
sumsung submitted, created time 7 months 2 weeks (www.sciam.com)
Smoking is the most potent known cause of lung cancer. The question is: Why do some longtime smokers come down with the deadly disease whereas others escape it? New research points to a genetic culprit that also was fingered as upping a person's likelihood of becoming hooked on cigarettes.
Two Resistance Genes for the Price of One--Ideal?
Sue Wu submitted, created time 7 months 3 weeks (sciencenow.sciencemag.org)
It seems like a no-brainer, even for mosquitoes: Why be resistant to one pesticide when you can be resistant to two? In practice, however, such adaptations weaken insects in other ways, so more might not be a good thing.
Starving before chemotherapy could save more lives
sumsung submitted, created time 8 months 1 day (www.newscientist.com)
Chemotherapy would have fewer side effects and save more lives if patients fasted for two days before receiving treatment, suggest tests in animals. Mice injected with cancerous cells and then given chemotherapy died after around 60 days. But animals that were starved for 48 hours prior to treatment typically lived 10-20 days longer, says Valter Longo of the University of Southern California in Davis, US. The longest-lived of the 16 mice that fasted did not die until around 14 weeks after being injected.
Race-specific cancer mutation found
jane2007 submitted, created time 8 months 1 day (www.nature.com)
Researchers have identified a specific genetic mutation raises the risk of colon cancer in Caucasians by 10% but not in Japanese.
Breast cancer gene carriers’ risk ‘amplified’ by additional genes
jane2007 submitted, created time 8 months 1 week (www.admin.cam.ac.uk)
According a new research, many women with a faulty breast cancer gene could be at greater risk of the disease due to extra, risk-amplifying genes.
Team Uncovers New Evidence of Recent Human Evolution
jane2007 submitted, created time 9 months 3 weeks (sciencenow.sciencemag.org)
By identifying 582 genes that have evolved differently in different populations in the past 60,000 years, including a dozen that protect people from obesity, diabetes, hypertension, and other diseases, researchers have found powerful new evidence of recent human evolution.
Don't It Make Your Brown Eyes Blue?
Eric wu submitted, created time 10 months 4 hours (sciencenow.sciencemag.org)
Blue-eyed? Thank a genetic switch that turns off your body's ability to make brown pigment in your peepers. Researchers have finally located the mutation that causes blue eyes, and the findings suggest that all blue-eyed humans share a single common ancestor born 6000 to 10,000 years ago.
"Normal" genes key to cancer growth
jane2007 submitted, created time 10 months 1 day (www.nature.com)
Geneticists have identified genes that are normally present and that seem to be key to the growth and survival of specific cancers. The finding, from a functional-genomics screen of human cells, could offer new drug targets for blitzing tumors.
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