Articles with the keyword: 
Molecular Motor Tied to Memory
sea-maid submitted, created time 2 months 6 days (sciencenow.sciencemag.org)
How does the brain record a memory? Somehow our experiences and interactions can be imprinted in the mind, but exactly how neurons alter their connections to enable memory has been murky. Now a team of researchers out of Duke University say they have identified the molecular machinery that links experience with learning--and it all comes down to one microscopic motor. 
Myosin I Can Act As a Molecular Force Sensor
jerry submitted, created time 6 months 2 days (www.sciencemag.org)
The ability to sense molecular tension is crucial for a wide array of cellular processes, including the detection of auditory stimuli, control of cell shape, and internalization and transport of membranes. We show that myosin I, a motor protein that has been implicated in powering key steps in these processes, dramatically alters its motile properties in response to tension. We measured the displacement generated by single myosin I molecules, and we determined the actin-attachment kinetics with varying tensions using an optical trap
MYPT1 regulates mitosis by antagonizing Plk1
jerry submitted, created time 7 months 2 weeks (www.developmentalcell.com)
This study identifies a previously unrecognized role of MYPT1 in regulating mitosis by antagonizing PLK1. MYPT1 binds to PP1C. This binding is believed to target PP1C to specific substrates including myosin II, thus controlling cellular contractility.
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