Fatal protein interactions may explain neurological diseases

sea-maid submitted, created time 2 months 4 weeks (esciencenews.com)

In a collaborative study at the University of California, San Diego, investigators from neurosciences, chemistry and medicine, as well as the San Diego Supercomputer Center (SDSC) have investigated how proteins involved in neurodegenerative diseases such as Alzheimer's and Parkinson's disease interact to form unique complexes. Their findings explain why Alzheimer's patients might develop Parkinson's, and vice versa. The new and unique molecular structures they discovered can now be used to model and develop new drugs for these devastating neurological diseases

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Differential neuroprotective and antiinflammatory effects of estrogen receptor (ER) and ER ligand treatment

davis submitted, created time 1 year 2 months (www.pnas.org)

Treatment with either estradiol or an estrogen receptor (ER) ligand has been shown to be both antiinflammatory and neuroprotective in a variety of neurological disease models, but whether neuroprotective effects could be observed in the absence of an antiinflammatory effect has remained unknown.

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