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Researchers discover that gene switches on during development of epilepsy

piggy submitted, created time 1 year 4 months (www.eurekalert.org)

A discovery made by researchers at Wake Forest University School of Medicine while studying mice may help explain how some people without a genetic predisposition to epilepsy can develop the disorder.

In a study published this month in the Journal of Neuroscience, senior researcher Dwayne W. Godwin, Ph.D

12

How the brain translates memory into action

piggy submitted, created time 1 year 4 months (www.eurekalert.org)

When we emerge from a supermarket laden down with bags and faced with a sea of vehicles, how do we remember where we've parked our car and translate the memory into the correct sequence of footsteps and shifts of weight to get back to it? A paper in this week's PLoS Biology identifies the specific parts of the brain responsible for solving this everyday problem. These results could have implications for understanding the functional significance of a prominent brain abnormality observed in neuropsychiatric diseases such as schizophrenia

12

Study identifies genes that protect against aging

piggy submitted, created time 1 year 4 months (www.eurekalert.org)

Scientists at the University of Liverpool have developed a new method to help researchers identify genes that can help protect the body during the aging process.

The team developed a method of analyzing genes in several types of aging tissue in both animals and humans. The analysis, which included more than five million gene measurements, highlighted the mechanisms used by the body to protect against age-related cellular changes that can result in muscle degeneration and cognitive aging

12

Closer Look at Einstein's Brain

piggy submitted, created time 1 year 4 months (sciencenow.sciencemag.org)

When a rare genius like Albert Einstein comes along, scientists naturally wonder if he had something special between his ears. The latest study of Einstein's brain concludes that certain parts of it were indeed very unusual and might explain how he was able to go where no physicist had gone before when he devised the theory of relativity and other groundbreaking insights. The findings also suggest that Einstein's famed love of music was reflected in the anatomy of his brain

9

Stem Cell Breakthrough May Lead to MS Treatments

sea-maid submitted, created time 1 year 4 months (news.yahoo.com)

U.S. scientists say they've coaxed human embryonic stem cells into generating cells that might someday be used to repair nerves damaged by multiple sclerosis.

12

Double Amputees Shed Light on Brain's Flexibility

piggy submitted, created time 1 year 4 months (sciencenow.sciencemag.org)

How does the brain cope when, several years after having both hands amputated, a person suddenly receives two new hands? Surprisingly well, it seems. In a study out today, researchers provide the most detailed picture yet of how the brain reorganizes itself to accommodate foreign appendages. And in a result that they are still trying to explain, the scientists found that in two such double-hand transplants, the left hand reconnected with the brain more quickly than did the right.

10

Nobel laureate's dream for brain research finds home

sea-maid submitted, created time 1 year 4 months (www.nature.com)

An Italian competition to host a European Brain Research Institute (EBRI) has been won by a private hospital in Rome.

12

Relief of itch by scratching: state-dependent inhibition of primate spinothalamic tract neurons

piggy submitted, created time 1 year 4 months (www.nature.com)

Itch is relieved by scratching, but the neural mechanisms that are responsible for this are unknown. Spinothalamic tract (STT) neurons respond to itch-producing agents and transmit pruritic information to the brain. This article reports observations that scratching the cutaneous receptive field of primate STT neurons produces inhibition during histamine-evoked activity but not during spontaneous activity or activity evoked by a painful stimulus, suggesting that scratching inhibits the transmission of itch in the spinal cord in a state-dependent manner.

10

Gene protects against neurotoxins that spur inflammation and Parkinson's disease

sea-maid submitted, created time 1 year 5 months (www.eurekalert.org)

A new study in the April 3rd issue of the journal Cell helps to explain why people who carry mutations in a gene known as Nurr1 develop a rare, inherited form of Parkinson's disease, the most prevalent movement disorder in people over the age of 65.

10

By Shutting Down Inflammation, Agent Reverses Damage from Spinal Cord Injury in Preclinical Studies

sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)

Researchers at Georgetown University Medical Center (GUMC) have been able to speed recovery and substantially reduce damage resulting from spinal cord injury in preclinical studies.

12

Test tube disease models one step closer

icecream submitted, created time 1 year 5 months (www.nature.com)

Skin cells from Parkinson's patients transformed into tailor-made neurons

9

Gulf War Veterans Display Abnormal Brain Response to Specific Chemicals

sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)

A new study by UT Southwestern Medical Center researchers is the first to pinpoint damage inside the brains of veterans suffering from Gulf War syndrome – a finding that links the illness to chemical exposures and may lead to diagnostic tests and treatments.

11

MIT: Blocked enzyme reverses schizophrenia-like symptoms

piggy submitted, created time 1 year 5 months (www.eurekalert.org)

Researchers at MIT's Picower Institute for Learning and Memory have found that inhibiting a key brain enzyme in mice reversed schizophrenia-like symptoms.

The finding, reported in the March 20 issue of Cell, identified how a particular gene controls this brain enzyme. Better understanding of the relationship could lead to new drug treatments for schizophrenia, a severe brain disorder characterized by hallucinations, delusions, poor social and emotional functioning and disorganized thoughts

10

Stem cell scaffold for stroke patients

sea-maid submitted, created time 1 year 5 months (news.bbc.co.uk)

Scientists have developed a tiny scaffold of stem cells to fill holes in the brain caused by stroke damage. The polymer scaffolds themselves, only a tenth of a millimeter wide, are designed to dissolve in the body after giving the stem cells enough time to integrate with the patient's damaged brain. In rats, the stem cell/scaffold combination was able to replace damaged tissue within a week. Adding a protein to the cocktail might also encourage the growth of new blood vessels.

9

Precise Communication Discovered Across Brain Areas During Sleep

sea-maid submitted, created time 1 year 5 months (www.sciencedaily.com)

By listening in on the chatter between neurons in various parts of the brain, researchers from the California Institute of Technology (Caltech) have taken steps toward fully understanding just how memories are formed, transferred, and ultimately stored in the brain--and how that process varies throughout the various stages of sleep.

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