Further review of "three-parent" embryo technique

Darkfrog submitted, created time 9 months 3 weeks (www.nature.com)

This is another discussion of the mother-father-mitochondiadonor embryo that I mentioned the other day. It is significantly more revealing. It seems that the mitochondrial transfer involved moving nuclear DNA from the diseased embryo to the healthy one instead of into an ovum from another source.

It also discusses their methods. It seems that the exchange was performed in embryos that had failed in other experiments. The ten successes came from many failures. The specific success to failure ratio is not given.

Submit comment | Blog It | Email It | Keywords: mitochondria mitochondrial DNA embryo embryos human reproduction fertility nuclear transfer somatic cell nuclear transfer nuclear DNA

Nuclear industry revival hits roadblocks

saury submitted, created time 1 year 5 months (www.newscientisttech.com)

The much-touted resurgence of the European nuclear industry, promoted as a local solution to climate change, is already running into trouble.

Submit comment | Blog It | Email It | Keywords: nuclear transplantation nuclear DNA

Molecular mechanism of the nuclear protein import cycle

amanda submitted, created time 1 year 8 months (www.nature.com)

The nuclear import of proteins through nuclear pore complexes (NPCs) illustrates how a complex biological function can be generated by a spatially and temporally organized cycle of interactions between cargoes, carriers and the Ran GTPase. Recent work has given considerable insight into this process, especially about how interactions are coordinated and the basis for the molecular recognition that underlies the process.

Submit comment | Blog It | Email It | Keywords: nuclear DNA nuclear permeability molecular interactions nuclear protein

The evolutionary history of human DNA transposons: Evidence for intense activity in the primate lineage

angelfish submitted, created time 1 year 8 months (www.genome.org)

“Class 2, or DNA transposons, make up 3% of the human genome, yet the evolutionary history of these elements has been largely overlooked and remains poorly understood. Here scientists carried out the first comprehensive analysis of the activity of human DNA transposons over the course of primate evolution using three independent computational methods. First, They conducted an exhaustive search for human DNA transposons nested within L1 and Alu elements known to be primate specific

Submit comment | Blog It | Email It | Keywords: human activity protein-DNA interactions nuclear DNA

Not Milk? Neolithic Europeans Couldn't Stomach the Stuff

catherine submitted, created time 1 year 9 months (www.sciam.com)

In what they claim is the first direct evidence of the evolution of lactase-persistence (the ability to digest milk and other dairy foods), German and British researchers came up empty in their search for the gene variant that allows over 90 percent of northern Europeans to gulp down and properly digest milk. In many others around the world, lactose causes diarrhea and bloating, especially in adulthood

Submit comment | Blog It | Email It | Keywords: gene Stomach Lactase nuclear DNA