Frozen mice cloned - are woolly mammoths next?

piggy submitted, created time 3 weeks 5 days (www.reuters.com)

WASHINGTON (Reuters) - Japanese scientists have cloned mice whose bodies were frozen for as long sixteen years and said on Monday it may be possible to use the technique to resurrect mammoths and other extinct species.

Mouse cloning expert Teruhiko Wakayama and colleagues at the Center for Developmental Biology, at Japan's RIKEN research institute in Yokohama, managed to clone the mice even though their cells had burst.

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Part human, part cow embryos made in UK

Further review of "three-parent" embryo technique

Darkfrog submitted, created time 9 months 3 weeks (www.nature.com)

This is another discussion of the mother-father-mitochondiadonor embryo that I mentioned the other day. It is significantly more revealing. It seems that the mitochondrial transfer involved moving nuclear DNA from the diseased embryo to the healthy one instead of into an ovum from another source.

It also discusses their methods. It seems that the exchange was performed in embryos that had failed in other experiments. The ten successes came from many failures. The specific success to failure ratio is not given.

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Cloning of endangered mammalian species: any progress?

medal submitted, created time 1 year 6 months (www.sciencedirect.com)

"Attempts through somatic cell nuclear transfer to expand wild populations that have shrunk to critical numbers is a logical extension of the successful cloning of mammals. However, although the first mammal was cloned 10 years ago, nuclear reprogramming remains phenomenological, with abnormal gene expression and epigenetic deregulation being associated with the cloning process

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