Nuclear industry revival hits roadblocks

saury submitted, created time 1 year 6 months (www.newscientisttech.com)

The much-touted resurgence of the European nuclear industry, promoted as a local solution to climate change, is already running into trouble.

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From Nuclear Transfer to Nuclear Reprogramming: The Reversal of Cell Differentiation

BIOBOSS submitted, created time 1 year 11 months (www.biology.ucsd.edu)

[Full Text] This is a personal historical account of events leading from the earliest success in vertebrate nuclear transfer to the current hope that nuclear reprogramming may facilitate cell replacement therapy. Early morphological evidence in Amphibia for the toti- or multipotentiality of some nuclei from differentiated cells first established the principle of the conservation of the genome during cell differentiation. Molecular markers show that many somatic cell nuclei are reprogrammed to an embryonic pattern of gene expression soon after nuclear transplantation to eggs

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