Articles with the keyword: 
Pfizer ends development of obesity drug
piggy submitted, created time 3 weeks 4 days (www.reuters.com)
NEW YORK, Nov 5 (Reuters) - Pfizer Inc on Wednesday became the latest drugmaker to abandon an obesity treatment that works by blocking the receptors in the brain that makes people hungry after smoking marijuana.
The world's largest drugmaker said it was terminating late stage development of its experimental obesity drug, CP-945,598, citing a more conservative regulatory climate and problems seen with other medicines from the same class 
GlaxoSmithKline's customized "red wine" drug potent in mice
piggy submitted, created time 3 weeks 4 days (www.reuters.com)
LONDON (Reuters) - A drug in development that mimics a health-boosting compound found in red wine may be a powerful weapon in the fight against obesity and diabetes, researchers said on Tuesday.
A study of mice showed that the GlaxoSmithKline drug SRT1720 was about a thousand times more potent than resveratrol in activating an enzyme that helped the animals burn more energy and lower their insulin and glucose levels
Bariatric surgery hangs up its scalpel
Darkfrog submitted, created time 1 month 1 week (www.nytimes.com)
In serious cases of obsity, patients sometimes opt for bariatric surgery--modifications to the stomach. This may include staples or cinchers, but the effect is that the stomach is shrunk so that the patient feels full after eating only a little. The surgical techniques involved have become more precise over the years, and many bariatric surgeries have been performed through only a tiny slit in the patient's abdominal wall
Identification of White Adipocyte Progenitor Cells in Vivo
sea-maid submitted, created time 1 month 2 weeks (www.cell.com)
The increased white adipose tissue (WAT) mass associated with obesity is the result of both hyperplasia and hypertrophy of adipocytes. However, the mechanisms controlling adipocyte number are unknown in part because the identity of the physiological adipocyte progenitor cells has not been defined in vivo. In this report, we employ a variety of approaches, including a noninvasive assay for following fat mass reconstitution in vivo, to identify a subpopulation of early adipocyte progenitor cells (Lin−:CD29+:CD34+:Sca-1+:CD24+) resident in adult WAT
Fat-regenerating "stem cells" found in mice
sea-maid submitted, created time 1 month 2 weeks (esciencenews.com)
Researchers have identified stem cells with the capacity to build fat, according to a report in the October 17th issue of the journal Cell, a Cell Press publication. Although they have yet to show that the cells can renew themselves, they have convirmed that they can renew fat tissue when transplanted into other animals.
Exercise Guidelines: Less Gym, More Fun
jerry submitted, created time 1 month 3 weeks (www.webmd.com)
New federal guidelines are more of the same. This article recommends at least 2.5 hours per week of moderate exercise or 1.25 hours per week of intense exercise for adults and gives examples. However, the newer note is that people, especially children, will be more likely to stick with the plan if the activity in question si fun.
Too Good to Be True? Fat That Keeps You Thin
sea-maid submitted, created time 2 months 1 week (www.sciam.com)
Scientists have stumbled on a chemical in the body that could one day prevent or reverse diseases linked to obesity.
Researchers at Harvard University's School of Public Health (H.S.P.H.) report in Cell that palmitoleate, a newly discovered hormone produced by fat cells, is also a fatty acid. (Most hormones are proteins
Fat Molecule Fights Weight Gain
jerry submitted, created time 2 months 1 week (sciencenow.sciencemag.org)
Rearchers have isolated a fat molecule in mice that prevents the animals from storing more fat. The discovery could open a new front in the battle against the bulge if the molecule has the same effect in humans.
The word "fat" typically evokes the image of clogged arteries or cellulite jiggling on a thigh. But fat has a good side, too. Fat cells make up adipose tissue, which helps regulate insulin levels and breaks down dietary fat for energy. This breakdown is accomplished via proteins in fat cells called fatty acidinding proteins
Surgery may help, but not cure, obese children with sleep disorders
sea-maid submitted, created time 2 months 1 week (esciencenews.com)
Surgical interventions for many obese children suffering from obstructive sleep apnea may not cure the problem, says new research presented at the 2008 American Academy of Otolaryngology – Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO in Chicago, IL. Obese children are at increased risk for developing obstructive sleep apnea (OSA), a sleep disorder that is associated with a decreased quality of life as well as behavioral, neurocognitive, cardiovascular, metabolic, endocrine, and psychiatric complications
Researchers Suppress "Hunger Hormone"
jerry submitted, created time 2 months 2 weeks (www.washingtonpost.com)
A minimally invasive procedure successfully suppressed levels of the "hunger hormone" ghrelin in pigs and led to appetite reduction results similar to bariatric surgery, say Johns Hopkins researchers.
Gastric Bypass Surgery Less Helpful for Diabetics
jerry submitted, created time 2 months 2 weeks (www.time.com)
A new study suggests that the common weight-loss surgery leads to less weight loss in patients with diabetes.
Study shows cost savings behind bariatric surgery
jerry submitted, created time 2 months 3 weeks (money.cnn.com)
Insurance companies do usually cover the costs of bariatric surgery, they would start now: A new study shows that, among morbidly obese patients, having a stomach stapling or an intestinal modification causes them to shed insurance claims as well as pounds.
The study looked at the insurance claims of 7200 morbidly obese patients, half of whom had had the surgery and half of whom had not
Prostate cancer risk increased in obese men who use statin drugs
kavin submitted, created time 3 months 1 day (www.reuters.com)
Use of cholesterol-lowering statin drugs, especially long-term use, appears to raise the risk of prostate cancer among obese men, according to findings of a new study.
"Given the epidemic of obesity in the U.S. and the frequent use of statins, the positive association we observed raises substantial concern as to the safety of these widely prescribed agents," Dr. Janet L. Stanford of the Fred Hutchinson Cancer Research Center in Seattle and colleagues wrote in the American Journal of Epidemiology
Fat Mum Hastens Path to Childhood Obesity
sea-maid submitted, created time 3 months 4 days (www.sciencedaily.com)
There is a correlation between children's obesity rates and those of their mothers, finds a new study. Other factors linked to a child's tendency to become obese include too much time spent in front of the TV and rapidly piling on the pounds in early childhood.
Boosting good fat to burn off the bad
sea-maid submitted, created time 3 months 6 days (www.nature.com)
To most dieters, no fat is good fat. But in work published this week in Nature, an insight into the origin of a special class of calorie-burning fat cells could lead to new ways of boosting metabolism and combating obesity, researchers say.
This article outlines research suggesting that brown fat cells, which convert energy into heat but remain otherwise mysterious, may not arise from the same tissue as our garden-variety white fat cells
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