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9

Genetic engineering makes pig organs ready for humans at last?

sea-maid submitted, created time 2 days 2 hours (www.newscientist.com)

In the not too distant future, a person in need of a heart transplant could be offered a pig's organ. That's the hope of a group that met in China last week to agree global guidelines for the first clinical trials of "xenotransplants."

There have been some serious problems that scientists have had to overcome. For example, porcine endogenous retroviruses, or PERVs, are one major concern. These are chunks of viral DNA incorporated into the pig genome. There are fears that these viruses could reawaken if they are transported into an unfamiliar body

12

Stem Cells Spawn First Drug-Free Windpipe Transplant

sea-maid submitted, created time 1 week 5 days (www.bloomberg.com)

Doctors operating on a 30-year-old Colombian woman restored her ability to breathe freely with the world's first transplanted windpipe specially treated to prevent organ rejection.

The airway connecting Claudia Castillo Sanchez's left lung to her windpipe collapsed after a persistent tuberculosis infection, leaving her short of breath and unable to perform routine daily activities. Efforts to prop it open failed, leaving Spanish doctors two options: remove the lung or replace the airway using an experimental technique tried only in animals

8

Growing blood in a dish

sea-maid submitted, created time 4 months 1 week (www.nature.com)

Developing a way to reliably produce hematopoietic stem cells is a bloody tough problem. Unlike most tissues, cells of the hematopoietic system emerge from several embryonic sites and then circulate through the body. This mobility has perplexed researchers, who hope that mimicking the in vivo environment will help them culture these stem cells. Now, two British research teams report in Cell Stem Cell their complementary techniques for isolating these cells. These methods could form the lifeblood of creating easier alternatives to bone marrow transplantation.

8

Singapore to examine kidney trading

sea-maid submitted, created time 4 months 1 week (news.yahoo.com)

Singapore is considering legalizing kidney trading to help meet demand for kidney transplants, the city-state's health minister said Monday

13

Be still my beating stem cell heart

sea-maid submitted, created time 6 months 3 weeks (www.newscientist.com)

There's a new recipe in the embryonic stem cell cookbook. Scientists have announced the creation of a human master heart cell, able to transform into all the different cells that make up a beating heart. In this study, the scientists have begun experiments to transform iPS cells into the heart cells.

12

Organ trafficking cracked down upon in the Phillippines

Darkfrog submitted, created time 7 months 1 day (www.nytimes.com)

Poor Filipinos can make between $2000 and $10,000 (USD) by selling kidneys to sick foreigners. This has been illegal for many years, but a sixty percent increase in illegal kidney "donations" between 2004 and 2006 has sparked the government of the Phillippines to forbid foreign kidney donations entirely. With the exception of foreigners related by blood to Filipino citizens, this part of the Phillippines' medical tourism industry is to come to an end.

19

Beating heart tissue produced in laboratories

sea-maid submitted, created time 7 months 1 week (www.nature.com)

An international team of researchers has used stem cells to create heart tissue, complete with beat. By treating embryonic stem cells with growth factors, they coaxed them into becoming cardiovascular progenitor cells, which then developed into cardiomyocytes, vascular smooth muscle cells, and endothelial cells, which together form blood vessels. When injected into the hearts of mice with induced heart disease, they improve heart function.

What this discovery does not include is fibroblasts, the cells that form the framework of the heart.

17

Embryonic stem cells coaxed into key heart cells

sumsung submitted, created time 7 months 1 week (www.sciam.com)

Scientists say they have coaxed human embryonic stem cells into becoming three of the major cell types in the human heart, and they improved cardiac function when transplanted into mice. The findings, published in the journal Nature on Wednesday, showed that scientists can efficiently make different kinds of human heart cells for use in basic and clinical research. The researchers said that in the short term, they could be used to test how heart cells respond to different drugs

5

Good News About Marrow Injections

Sue Wu submitted, created time 10 months 1 week (www.reuters.com)

Los Angeles patient Derek Besenfelder, who received a kidney transplant from his mother along with a bone marrow three years ago, has been able to discontinue taking anti-rejections drugs.

7

Organ transplants without rejection

jane2007 submitted, created time 10 months 1 week (www.nature.com)

Three independent research teams have successfully performed organ transplantations that do not require the recipient to face a lifetime of immunosuppressant drugs to prevent rejection. Instead, the new techniques prevent rejection by training the immune system to recognize the new organ as its own.

5

Lung transplants no help for cystic fibrosis!

Eric wu submitted, created time 1 year 1 week (www.reuters.com)

Children with severe cystic fibrosis are seldom helped by a lung transplant, researchers said on Wednesday in findings they said stunned them.

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