Articles with the keyword: 
The Pill and Ovarian Cancer: Persistent Protection
kavin submitted, created time 4 months 2 weeks (womens-health.jwatch.org)
Reanalysis of forty-five studies verifies that oral contraceptives provide protection when women need it most, decades after use.
Although oral contraceptives (OCs) have been shown to reduce the risk for epithelial ovarian cancer, the duration of this protective effect has not been clearly defined. Now, investigators have reanalyzed data from forty-five case-control and prospective studies (primarily in Europe and the U.S.) including more than 23,000 women with ovarian cancer (cases; mean age at diagnosis, 56) and 87,000 women without the disease (controls) 
Symptoms Plus Blood Test Boost Ovarian Cancer Detection
lily1984 submitted, created time 5 months 1 week (www.washingtonpost.com)
U.S. researchers boosted the level of early-stage ovarian cancer detection by 20 percent through use of a blood test to detect a tumor marker as well as a woman's report of new-onset symptoms.
Using either test alone only uncovered about 60 percent of early-stage ovarian cancers in a high-risk group of women, while the two techniques together found 80 percent of early-stage tumors, according to finding published Monday in the online version of the journalCancer
The birth control pill linked to reduced ovarian cancer risk
Sue Wu submitted, created time 10 months 4 days (seattlepi.nwsource.com)
The longer a woman uses the oral contraceptive pill, the lower her risk of getting ovarian cancer later in life, the Lancet medical journal reports.
Breast Cancer Gene Might Extend Ovarian Cancer Survival
Sue Wu submitted, created time 10 months 3 weeks (www.medicinenet.com)
After five years of following a group of Ashkenazi Jewish women with ovarian cancer, researchers reported that women with the BRCA1 or 2 mutations were 29 percent less likely to die from the disease.
brooke submitted, created time 1 year 1 month (www.pnas.org)
Ovarian cancer is a leading cause of deaths, yet many aspects of the biology of the disease and a routine means of its detection are lacking. We have used protein microarrays and autoantibodies from cancer patients to identify proteins that are aberrantly expressed in ovarian tissue.
007RA submitted, created time 1 year 3 months (vasectomy.researchtoday.net)
"ovarian cancer, it is unclear how long this protection persists. The authors prospectively assessed this question as well as associations of other, less studied contraceptive methods (tubal ligation, rhythm method, diaphragm, condoms, intrauterine device, foam, spousal vasectomy) and infertility with ovarian cancer risk among 107,900 participants in the US Nurses' Health Study. During 28 years of follow-up (1976-2004), 612 cases of invasive epithelial ovarian cancer were confirmed."
Effectiveness of Chemotherapy For Ovarian Cancer Improved By Cranberry Compounds
guohong submitted, created time 1 year 3 months (www.medicalnewstoday.com)
At the 234th national meeting of the American Chemical Society, the sciensts said that compounds in cranberries may help improve the effectiveness of platinum drugs that are used in chemotherapy to fight ovarian cancer. They demonstrated in cell culture studies that human ovarian cancer cells resistant to platinum drugs became up to 6 times more sensitized to the drugs after exposure to the cranberry compounds in comparison to cells that were not exposed to the compounds, which were obtained from juice extracts
sumsung submitted, created time 1 year 4 months (www.pnas.org)
NY-ESO-1 is a "cancer-testis" antigen expressed in epithelial ovarian cancer (EOC) and is among the most immunogenic tumor antigens defined to date.
Scientists take next step in understanding potential target for Ovarian cancer treatment
bianjie submitted, created time 1 year 4 months (www.eurekalert.org)
A traffic cop protein in the cell may have an even more important role: transporting a messenger protein that tells components in the nucleus to stop cell growth. Scientists are studying the normal function of a protein called 'km23', the traffic cop protein, because the team previously found altered forms of the protein in 42 percent of tumor tissue samples taken from women with Ovarian cancer. The discovery of this additional role may lead to diagnostic tools and earlier treatments for Ovarian cancer.
Survivors of rare ovarian cancer retain fertility, have positive relationships, study finds
BIOBOSS submitted, created time 1 year 5 months (www.eurekalert.org)
Ovarian germ cell tumor patients treated with platinum-based chemotherapy and fertility-sparing surgery are likely to retain their menstrual function and reproductive ability, according to the largest and most comprehensive survey of survivors ever conducted.
DanyC submitted, created time 1 year 5 months (www.mcponline.org)
"Small GTPase RAS plays a critical role in cellular signaling and oncogenic transformation. Proteomics analysis of genetically defined human ovarian cancer models identified the tumor susceptibility gene 101 (TSG101) as a downstream target of RAS oncogene. Mechanistic studies revealed a novel post-translational regulation of TSG101 through the RAS/RAF/MEK/MAPK signaling pathway and downstream molecules p14ARF/HDM2. Immunoanalysis using ovarian cancer samples and microtissue array revealed elevated TSG101 levels in human ovarian carcinomas
Reviver submitted, created time 1 year 5 months (www.clinchem.org)
"Researchers discovered several biomarker panels that enabled differentiation of stage I ovarian cancer from unaffected (age-matched) patients with no evidence of ovarian cancer, with positive results in >93% of samples from patients with disease-negative results and in 97% of disease-free controls. The carrier protein–based approach identified additional protein fragments, many from low-abundance proteins or proteins not previously seen in serum."
Possible early signs of ovarian cancer identified
bioman submitted, created time 1 year 5 months (www.cnn.com)
Certain symptoms alone or in combination might alert women to ovarian cancer. Signs: sudden bloating, frequent urination, eating changes, abdominal pain. American Cancer Society, other groups agree on list of symptoms. Previously experts believed there were no early signs of ovarian cancer.
Chemotherapy Thwarted by Cancer-Killing Gene
badboy submitted, created time 1 year 6 months (www.sciam.com)
"A study of ovarian cancer patients undergoing chemotherapy determined that individuals with a mutant, nonfunctional version of the tumor-suppressing gene p53 had a survival rate more than twice as high as counterparts with a properly functioning gene. This, despite the fact that the gene in question is, under normal circumstances, essential for preventing cancer in the first place. "
Lessons From Ovarian Cells Migration: The Three "Ws" Of Ovarian Cancer Spreading
psychologist submitted, created time 1 year 6 months (www.medicalnewstoday.com)
Who must go? When to go? Where to go? During development ovarian cells migrate in a spacial-temporal coordinated way, responding to specific signals that determine which cells have to move, when they have to move, and where they have to go. The same types of signals stimulate migration of ovarian cancer cells, which follow specific signals to move from the female genital tract towards the peritoneum and stroma, where they form metastases
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