Articles with the keyword:
10

They're calling it "biological alchemy": induced stem cells proliferate

sea-maid submitted, created time 4 months 1 week (www.newscientist.com)

CALL it biological alchemy: specialist pancreatic cells that secrete digestive enzymes have been converted directly into insulin-producing beta cells. Meanwhile, epithelial cells from the back of the eye have been coaxed into becoming a versatile, new type of stem cell.

Both advances, reported last week in Philadelphia, Pennsylvania, at the annual meeting of the International Society for Stem Cell Research (ISSCR), may take us closer to a "regenerative" approach to repairing damaged tissue

8

Five new proteins for detecting pancreatic cancer early

kavin submitted, created time 4 months 3 weeks (medicine.plosjournals.org)

NEW YORK (Reuters Health) Jun 18 - Proteins differentially expressed in a mouse model of pancreatic ductal adenocarcinoma are also present in early-stage disease in humans, scientists report in the June issue of PLoS Medicine.

"There is a compelling need to develop blood-based markers that allow early cancer detection, classify tumors to direct therapy, and monitor disease progression, regression, or recurrence," senior author Dr. Samir M. Hanash, at the Fred Hutchinson Cancer Research Center in Seattle, and his colleagues write

5

Equivalent of a death sentence : Pancreatic cancer

DanyC submitted, created time 8 months 1 week (www.stuff.co.nz)

Woo...I have shocked by such new, anyone, who have heard such like below:
Most pancreatic cancer patients are dead within the first year.
Common symptoms of the cancer include appetite loss, weight loss, upset stomach and nausea. The most common physical sign can be jaundice.

7

Pigs Could Be the Salvation of Diabetes Sufferers

sumsung submitted, created time 9 months 2 weeks (www.sciam.com)

Most people probably view pigs at best as a source of sustenance or, at worst, as filthy, gluttonous animals. But it seems our porcine pals may also prove invaluable in the fight against type 1 diabetes. Researchers are experimenting with new ways of harvesting insulin-producing islet cells from pigs and transplanting them into diabetes sufferers in the hope of one day reducing the need for daily insulin shots and even replacing them with twice-yearly islet-cell treatments.

7

Cell regeneration brings hope for diabetics

jane2007 submitted, created time 9 months 3 weeks (www.nature.com)

Some cells in the adult pancreas can, in times of extreme stress, produce new insulin-secreting cells, researchers have found. The findings, based on work performed in mice, open up a new approach to replacing insulin-secreting cells in patients with diabetes.

8

Hurt an Organ, Help a Disease?

Eric wu submitted, created time 9 months 3 weeks (sciencenow.sciencemag.org)

Researchers report that by injuring an animal's pancreas, they have found a population of cells that naturally become insulin-producers. It's not clear whether the find will impact diabetes patients, but researchers are intrigued by the discovery and what it might reveal about the transformative ability of pancreatic cells.

7

The Long Road to Beta Cells

Eric wu submitted, created time 10 months 3 weeks (www.sciencenews.org)

In 2000, researchers in Canada reported a possible breakthrough in the treatment of type 1 diabetes. By transfusing insulin-producing cells from donated pancreases into patients, the researchers provided what looked like cures. Within a week after the procedure, all of the first six patients were liberated from daily insulin injections.

6

Selenium status alters tumour differentiation but not incidence or latency of pancreatic adenocarcinomas in Ela-TGF- p53+/– mice

jiangyun submitted, created time 1 year 2 months (carcin.oxfordjournals.org)

Pancreatic carcinoma has so far not been tested as an end point in such studies. We thus investigated the influence of supplemental nutritive selenium on pancreatic carcinogenesis in selenium deficient animals by use of a genetically defined disease model. Over a period of 800 days, all animals (n = 131) in the study developed tumours.

5

Photosynthetic oxygen generator for bio-artificial pancreas

bloch submitted, created time 1 year 4 months (www.beta-o2.com)

This artickle discibed new original aparoach for oxygen supply to bio-artificial pancreas

7

Cx36-Mediated Coupling Reduces ß-Cell Heterogeneity, Confines the Stimulating Glucose Concentration Range, and Affects Insulin Release Kinetics

athena submitted, created time 1 year 7 months (diabetes.diabetesjournals.org)

"We studied the effect of gap junctional coupling on the excitability of ß-cells in slices of pancreas, which provide a normal environment for islet cells. The electrophysiological properties of ß-cells from mice (C57Bl/6 background) lacking the gap junction protein connexin36 (Cx36–/–) were compared with heterozygous (Cx36+/–) and wild-type littermates (Cx36+/+) and with frequently used wild-type NMRI mice."

3

Maternal Cells in Child

Cassidy submitted, created time 1 year 9 months (www.medgadget.com)

It has been known for some years that mother and baby exchange stem cells in the course of pregnancy, and that these may live on for many years, apparently tolerated by the new host. The phenomenon is known as microchimerism, and it is still unclear as to whether the presence of such cells can be harmful to the recipient.
A Bristol team has looked for maternal cells in children with type 1 diabetes, an immune-mediated disorder, and found that around 20 per cent of these children have unusually high levels of maternal DNA in their circulation

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