Articles with the keyword: 


Brain implant allows mute man to speak
sea-maid submitted, created time 1 week 1 day (www.nature.com)
An electrode implanted into the brain of a man with locked-in syndrome has enabled him to use a speech synthesizer to produce vowel sounds as he thinks them. The same team is now working on a chip that can also produce consonants.
Locked-in syndrome is a type of paralysis in which patients are unable to voluntarily move anything but their eyelids. However, they are fully conscious 


Brain–machine interfaces: Back in control
sea-maid submitted, created time 1 week 5 days (www.nature.com)
Spinal cord injury disrupts the pathway between brain and muscle, causing paralysis. One potential strategy for treatment is to use a brain–machine interface to route control signals from the brain directly to the muscles, bypassing the site of injury. For the first time, Moritz and colleagues have shown that an artificial device can compensate for paralysis in monkeys 


Coaxing Injured Nerves to Regrow
piggy submitted, created time 3 weeks 4 days (sciencenow.sciencemag.org)
The adult central nervous system has only a limited ability to repair itself. That's why spinal cord injuries leave people permanently paralyzed. Now a study with mice finds that removing a particular signaling molecule in adult neurons restores their ability to regenerate damaged axons, the long extensions that convey signals from one neuron to another. The find potentially paves the way for repairing spinal cords and other nervous system injuries 


Nerve stem cells coaxed into working nerve cells
Darkfrog submitted, created time 5 months 2 weeks (www.medicalnewstoday.com)
Researchers at the UT Southwestern Medical Center have found a number of small compounds that stimulate nerve stem cells to develop into nerve cells. They synthesized a version that they are calling isoxazole-9, or ISX-9. This compound seems to have applications in nerve damage and brain cancer chemotheryapy. 


Stem cell researchers face down stem cell tourism
sea-maid submitted, created time 5 months 3 weeks (www.nature.com)
"Stem cell tourism," in which people travel thousands of miles and pay thousands of dollars to receive unregulated care, is nothing new. Now, with more stem cell applications being pushed toward clinical trials, the international research community is stepping up.
Although some of the patients report positive results, the fact that they cannot describe their treatments in detail--or produce verifiable medical records--severely limits the research value (though not the human value) of their cases 


Monkeys show amazing learning curve with thought-controlled prosthetics
Darkfrog submitted, created time 6 months 2 days (www.nytimes.com)
Monkeys with small (as in a mm or so wide) grid implanted just beneath their skulls have shown themselves able to control a mechanical arm with their thoughts.
This is an NYT writeup of an article originally published in Nature. Scientists first taught the monkeys how to control a mechanical arm with a joystick, then implanted a small grid, only a mm or so wide, onto the motor centers of their brains. The monkeys' own arms were then gently restrained. The scientists used a computer to move the arm at first. The article uses the expression, "teaching with biofeedback 


Stem cell therapy clinical trial halted by the FDA
Darkfrog submitted, created time 6 months 1 week (www.nature.com)
The FDA has put the brakes on a clinical trial, mentioned on DiscoveR8 a few months ago: Geron company in California wants to inject the spines of spinal injury patients with oligodendroglial progenitor cells grown from embryonic stem cells.
At first I thought, "Good, a little caution never hurt anyone," but then I read that this trial has been in the works for four years. You know what? That four-year delay probably has hurt someone.
The FDA has NOT STATED ITS REASONS for the delay 


Eating disorders linked to narcolepsy
DanyC submitted, created time 8 months 3 weeks (www.upi.com)
Excessive day sleepiness/sleep paralysis -- experience several symptoms of eating disorders, a Dutch study says.
we will clear after know that from this news: narcolepsy is not just a sleeping disorder, but a hypothalamic disease with a much broader symptom profile 


Charles submitted, created time 10 months 1 week (www.ajhg.org)
The hereditary spastic paraplegias (HSPs [MIM 182601]) encompass a clinically heterogeneous group of neurodegenerative diseases characterized by a progressive degeneration of upper motor neurons.1 The cardinal clinical feature of lower extremity weakness and spasticity may occur in isolation (“pure” HSP) or be accompanied by other symptoms including mental retardation, cerebellar ataxia, optic and peripheral neuropathy, and thin corpus callosum 


Scientists Help Mice Paralyzed by Spinal Injuries Walk Again
Sue Wu submitted, created time 10 months 3 weeks (www.nature.com)
Scientists said they've learned more about the natural mechanisms that enable mice, humans and other animals regain spinal function after paralyzing spinal cord injuries, according to a study published in this week's edition of the journal Nature Medicine. There was also a writeup in Fox News
(http://www.foxnews.com/story/0,2933,320537,00.html) 


Simple Injection Shows Promise for Treating Paralysis
deirdre submitted, created time 1 year 7 months (www.livescience.com)
Paralyzed lab rodents with spinal cord injuries apparently regained some ability to walk six weeks after a simple injection of biodegradable soap-like molecules that helped nerves regenerate. The research could have implications for humans with similar injuries. 
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