Sequencing single molecules of DNA

jane2007 submitted, created time 9 months 3 days (www.nature.com)

A machine produced by Helicos BioSciences is the first of a new generation of devices, called single-molecule DNA sequencers, to enter the market. It can read individual letters from single molecules of DNA.

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Assessing the Determinants of Evolutionary Rates in the Presence of Noise

julie submitted, created time 1 year 7 months (mbe.oxfordjournals.org)

"Although protein sequences are known to evolve at vastly different rates, little is known about what determines their rate of evolution."

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Smaller, cheaper, faster PCR

jsmith submitted, created time 1 year 7 months (www3.interscience.wiley.com)

A pocket size thermal cycler relying on convection between heat sources at fixed temperature shows promising levels of amplification after only 10 minutes of PCR.

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Genenext term capture and random amplification for quantitative recovery of homo

laoheqon submitted, created time 1 year 11 months (www.sciencedirect.com)

The polymerase chain reaction (PCR) is instrumental in molecular analysis of microorganisms, allowing for the selective amplification of nucleic acids directly from clinical and environmental samples. However, the principles that allow for targeted amplification of DNA become a hindrance when attempting to simultaneously discriminate and quantify complex mixtures of homologous previous termgenes.next term Here we present a simple solution to the quantitative problem by separating the enrichment and amplification aspects of a conventional PCR reaction

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