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In Vivo Migration: A Germ Cell Perspective

BIOBOSS submitted, created time 1 year 11 months (www.biology.ucsd.edu)

[Full Text]The basic concepts of the molecular machinery that mediates cell migration have been gleaned from cell culture systems. However, the three-dimensional environment within an organism presents migrating cells with a much greater challenge. They must move between and among other cells while interpreting multiple attractive and repulsive cues to choose their proper path. They must coordinate their cell adhesion with their surroundings and know when to start and stop moving

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