Biological principles of microRNA-mediated regulation: shared themes amid diversity

sea-maid submitted, created time 2 months 2 weeks (www.nature.com)

Regulation of gene activity by microRNAs is critical to myriad aspects of eukaryotic development and physiology. Amidst an extensive regulatory web that is predicted to involve thousands of transcripts, emergent themes are now beginning to illustrate how microRNAs have been incorporated into diverse settings. These include potent inhibition of individual key targets, fine-tuning of target activity, the coordinated regulation of target batteries, and the reversibility of some aspects of microRNA-mediated repression

1 comment | Blog It | Email It | Keywords: microRNA miRNA point inhibition