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Irradiation-Induced Proapoptotic Gene Expression is Controled by the Differentiation in Drosophila Embryos

jerry submitted, created time 7 months 4 weeks (www.developmentalcell.com)

Surprisingly, sensitive-to-resistant transition happened in post-stage-12 embryos when they are irradiated.

The magic key of this is in the irradiation-responsive enhancer regions of the proapoptotic genes. It becomes enriched for trimethylated H3K27/H3K9 and forms a heterochromatin-like structure during the sensitive-to-resistant transition.

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