Cancer as a “Mitochondriopathy”

MedUnion submitted, created time 1 year 6 months (www.mupnet.com)

Mitochondria are subcellular organelles, whose well-known function is to produce ATP through the oxidative phosphorylation system. Alterations in respiratory activity and mitochondrial DNA (mtDNA) appear to be a general feature of malignant cells. The presence of mtDNA mutations has been reported in various cancer cells, and the abundance of mtDNA damage is consistent with the intrinsic susceptibility to constitutive oxidative stress

Submit comment | Blog It | Email It | Keywords: mtDNA mitochondria cancer prohibitin homoplasmy