Articles with the keyword: 


FDA: Epilepsy drug may be risky for Asians
piggy submitted, created time 1 month 1 week (www.fda.gov)
FDA is investigating new preliminary data regarding a potential increased risk of serious skin reactions including Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) from phenytoin therapy in Asian patients positive for a particular human leukocyte antigen (HLA) allele, HLA-B*1502. This allele occurs almost exclusively in patients with ancestry across broad areas of Asia, including Han Chinese, Filipinos, Malaysians, South Asian Indians, and Thais 


Epilepsy drug may be risky for Asians
sea-maid submitted, created time 1 month 1 week (news.yahoo.com)
Treatment with certain epilepsy drugs may expose some Asian patients to serious skin reactions, federal health officials warned Monday.
The Food and Drug Administration said it is investigating whether medications like Dilantin, Phenytek and Cerebyx, which are used to control epileptic seizures, can lead to severe skin blisters and bleeding for some Asian patients.
Patients who test positive for a gene known as HLA-B1502 appear to be at increased risk of developing the skin problems, preliminary data indicate 


Genetic testing may not be the best way to study one's ancestry
Darkfrog submitted, created time 1 month 3 weeks (www.nature.com)
In recent years, companies providing personal genetic exams have sprung up like mushrooms. For a fee and a cheek swab, they can will identify the client's countries of ancestry, even to specific regions.
However, Charmaine Royal of the the Duke Institute for Genome Sciences has serious reservations:
"The general limitation, I'd say, of all of these tests, is that they can't pinpoint with 100% accuracy who your ancestors may or may not be. Some people are concerned that the biogeographical ancestry test reifies the notion of race 


Bradley Effect abstains from 2008 election
Darkfrog submitted, created time 2 months 1 day (www.nytimes.com)
This year's election day showed record turnout among voters, but there was one factor that didn't show up at the polls: The Bradley Effect.
The Bradley Effect is a phenomenon that occurs when a black or other minority candidate runs for political office. The idea is that more people will be willing to vote against a minority candidate in the privacy of the voting booth than will be willing to admit it to pollsters face-to-face. It is named after a Tom Bradley, a black Californian who lost the 1982 race for governor despite polls predicting that he would win 


HIV in the U.S. hits American blacks extra hard
Darkfrog submitted, created time 3 months 3 weeks (www.nytimes.com)
The CDC has released a report on the way HIV spreads in the United States. Again, American blacks are at disproportionately high risk. While caucasian gay and bisexual men tend to get infected int heir thirties and forties, black gay and bisexual men tend to get infected in their teens and twenties.
The writeup does not say whether they adjusted for socioeconomic factors, but they do assert that the infected blacks were no more likely to be drug users or to engage in risky sexual behaviors than their counterparts in other races 


Narrowing World Health Disparities
sea-maid submitted, created time 4 months 6 days (www.time.com)
A sweeping new report by the World Health Organization's Commission on Social Determinants of Health challenges governments to improve world health through smart social policy. 


Black Americans have higher rates of HIV than some African countries
Darkfrog submitted, created time 5 months 1 week (www.nytimes.com)
According to the Black AIDS Institute, the United States may have a lower incidence of HIV than other countries overall, but U.S. blacks, considered alone, aren't so lucky. With 600,000 African-Americans living with HIV and 30,000 new infections each year, if American blacks were a country on their own, they would rank sixteenth worldwide. What's more, infected blacks are much more likely to die than infected whites, after adjusting for age (the article does not say that it adjusted for socioeconomic status) 


HIV gene is a mixed blessing for carriers
sea-maid submitted, created time 5 months 2 weeks (www.newscientist.com)
A GENETIC mutation common in African Americans slows the progression of HIV, yet paradoxically increases the risk of contracting the virus in the first place.
A clue that race-specific genes are involved in HIV came in 2002, when Sunil Ahuja of the University of Texas Health Science Center in San Antonio and colleagues discovered a mutation in the CCL5 gene that accelerates the progression of HIV-1, the most common form of the virus. Though the mutation was found in people of all races, it only accelerated the disease in Americans of European descent 


jerry submitted, created time 6 months 4 weeks (www.time.com)
A study finds that white patients on average fare better than black patients treated by the same doctors. No previous study has managed to adjust for the patient's economic situation in this way. Age, gender, obesity levels, everything was taken into account. The white patients fared better across the board.
One hypothesis seems most likely to be correct: It isn't that the doctors aren't treating the patients the same, but that they are. The patients from each subculture, says Thomas Sequist, face different challenges in sticking to their food and exercise regimens. 
davidd submitted, created time 8 months 2 weeks (sciencenow.sciencemag.org)
Scientists have discovered a genetic mutation that could explain why clinical trials of beta blockers have shown little benefit to African-American patients. Beta blockers block adrenaline receptors and slow heart rate, which can ease heart failure. 


Race-specific cancer mutation found
jane2007 submitted, created time 9 months 1 week (www.nature.com)
Researchers have identified a specific genetic mutation raises the risk of colon cancer in Caucasians by 10% but not in Japanese. 


DNA Pioneer’s Genome Blurs Race Lines
jane2007 submitted, created time 1 year 3 weeks (www.nytimes.com)
James D. Watson, the co-discoverer of the structure of DNA and winner of the Nobel prize, raised a storm recently when a British newspaper quoted him saying that black Africans are not as intelligent as whites. But his own brilliant DNA seems to blur the lines. 


DNA Tests Find Branches but Few Roots
jane2007 submitted, created time 1 year 1 month (www.nytimes.com)
HENRY LOUIS GATES JR., whose PBS special “African American Lives” explores the ancestry of famous African-Americans using DNA testing, recently has become one of the industry’s critics.The nest story is the reason: Mr. Gates says his concerns date back to 2000, when a company told him his maternal ancestry could most likely be traced back to Egypt, probably to the Nubian ethnic group. Five years later, however, a test by a second company startled him. It concluded that his maternal ancestors were not Nubian or even African, but most likely Europea 
Study shows smoking accelerates men's hair loss
Eric wu submitted, created time 1 year 1 month (www.reuters.com)
While Asian men generally have less trouble than Caucasians with the most common form of hereditary male baldness, smoking cigarettes may erase that edge, researchers said on Monday. 
Eric wu submitted, created time 1 year 1 month (sciencenow.sciencemag.org)
In colonial America, slaves from west Africa made many a plantation owner rich by growing a particular high-quality variety of rice. Now, genetic research suggests the slaves not only supplied the labor and the agricultural skills they'd gained in their home countries but also may have brought the valuable crop with them. 