Articles with the keyword:
12

Food Can Affect a Cell in the Same Way Hormones Do

piggy submitted, created time 4 weeks 2 days (www.eurekalert.org)

VIB researchers connected to the Katholieke Universiteit Leuven have discovered an important new mechanism with which cells can detect nutrients. This happens in the same way--and with the same effects--as when cells receive a message from a hormone. This finding can teach us more about how food affects our body. Furthermore, it can form the basis for new candidate targets for medicines.

Receptors
Every living thing is composed of cells and, via receptor proteins on their outer surface, cells communicate with each other and with the outside world

8

Enzyme reinforces tumor-causing role of the nuclear coactivator SRC-3

jane2007 submitted, created time 10 months 1 week (www.bcm.edu)

A new study shows, high levels of the enzyme atypical protein kinase C (aPKC) increases the activity of the cancer-associated protein steroid receptor coactivator-3 (SRC-3) in cancer cells that depend on estrogen to promote their growth.

7

New Advance in Understanding HIV

Sue Wu submitted, created time 10 months 3 weeks (www.efluxmedia.com)

Government scientists have discovered a new way in which H.I.V. attacks human cells, an advance that could provide fresh avenues for the development of additional therapies to stop AIDS, they reported on Sunday.

5

Proteins That Could Be Used to Halt HIV Are Identified

Sue Wu submitted, created time 11 months 4 weeks (www.washingtonpost.com)

A research team announced yesterday that it has identified about 270 human proteins that the AIDS virus apparently needs to infect a person, instantly providing researchers with dozens of new strategies for blocking or aborting HIV infection.

7

HIV helpers can be hijacked

jane2007 submitted, created time 11 months 4 weeks (www.nature.com)

This article open a door for us to cure HIV. Researchers have now identified over 250 of the human proteins that are needed by HIV to help it spread throughout the body, providing a treasure trove of potential HIV drug targets. In other words, the proteins needed by HIV will become the killer helper of HIV drugs.

7

Proteins That AIDS Virus Preys On

sumsung submitted, created time 11 months 4 weeks (www.time.com)

The AIDS virus has to hijack human proteins to do its damage, but scientists until now have known only a few dozen of its targets. On Thursday, Harvard researchers unveiled a surprisingly longer list, an important first step in the hunt for new drugs.

6

Turning on cells with magnetic switches

jane2007 submitted, created time 1 year 1 week (harvardscience.harvard.edu)

Harvard scientists have figured out how to turn cells on and off using magnets, an advance with potentially broad applications as researchers around the world work to find new ways to manipulate cells and correct cellular functions that diseases send awry.

18

Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells

scott submitted, created time 1 year 2 months (www.pnas.org)

The T cell receptor (TCR) expressed on most T cells is a protein complex consisting of TCRαβ heterodimers that bind antigen and cluster of differentiation (CD) 3εδ,εγ,and ζζ dimers that initiate signaling.

5

Towards a muscarinic hypothesis of schizophrenia

addict submitted, created time 1 year 8 months (www.nature.com)

Although the neurotransmitter dopamine plays a prominent role in the pathogenesis and treatment of schizophrenia, the dopamine hypothesis of schizophrenia fails to explain all aspects of this disorder. This review will focus on evidence that supports the hypothesis that the muscarinic system is involved in the pathogenesis of schizophrenia and that muscarinic receptors may represent promising novel targets for the treatment of this disorder.

5

Whatever turns you on: accessory-cell-dependent activation of NK cells by pathogens

Luneetty submitted, created time 1 year 9 months (www.nature.com)

Natural killer (NK) cells have a crucial role in combating infections and cancers and their surface receptors can directly recognize and respond to damaged, transformed or non-self cells. Whereas some virus-infected cells are recognized by this same route, NK-cell responses to many pathogens are triggered by a different mechanism. Activation of NK cells by these pathogens requires the presence of accessory cells such as monocytes, macrophages and dendritic cells

6

Cooperation of Toll-like receptor signals in innate immune defence

athena submitted, created time 1 year 9 months (www.nature.com)

The mechanisms by which the recognition of Toll-like receptor (TLR) ligands leads to host immunity remain poorly defined.

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