Articles with the keyword:
10

Pure Insulin-Producing Cells Produced in Mice

piggy submitted, created time 1 month 2 weeks (www.sciencedaily.com)

Singapore researchers have developed an unlimited number of pure insulin-producing cells from mouse embryonic stem cells (ESCs).

These pure insulin-producing cells, which according to electron microscopy studies, have the same sub-cellular structures as the insulin-producing cells naturally found in the pancreas, were highly effective in treating diabetes in the mouse model.

The transplants of pure insulin-producing cells reduced the blood glucose levels of diabetic mice with high blood glucose levels

12

Stem Cells Spawn First Drug-Free Windpipe Transplant

sea-maid submitted, created time 1 month 2 weeks (www.bloomberg.com)

Doctors operating on a 30-year-old Colombian woman restored her ability to breathe freely with the world's first transplanted windpipe specially treated to prevent organ rejection.

The airway connecting Claudia Castillo Sanchez's left lung to her windpipe collapsed after a persistent tuberculosis infection, leaving her short of breath and unable to perform routine daily activities. Efforts to prop it open failed, leaving Spanish doctors two options: remove the lung or replace the airway using an experimental technique tried only in animals

10

Tissue engineering triumph: Doctors transplant a trachea made from the patient's own stem cells

Darkfrog submitted, created time 1 month 2 weeks (www.lancet.com)

The medical journal Lancet has just announced that doctors have performed the first successful trachea transplant using a trachea crafted from the patient's own stem cells. The New York Times is hailing this as a revolutionary step in regenerative medicine. The surgery took place in Barcelona this past June. Researchers from universities in Spain, Britain and Italy collaborated on the preparation. The patient's original trachea--actually one of her bronchi--had been damaged by severe tuberculosis.

Prof

14

Stem Cells with Potential to Regenerate Injured Liver Tissue Identified

sea-maid submitted, created time 1 month 3 weeks (www.sciencedaily.com)

A novel protein marker has been found that identifies rare adult liver stem cells, whose ability to regenerate injured liver tissue has the potential for cell-replacement therapy. For the first time, researchers at the University of Pennsylvania School of Medicine led by Linda Greenbaum, MD, Assistant Professor of Medicine in the Division of Gastroenterology, have demonstrated that cells expressing the marker can differentiate into both liver cells and cells that line the bile duct.

This discovery could have serious implication for transplants and regenerative medicine

8

Umbilical Cord Blood May Help Build New Heart Valves

sea-maid submitted, created time 1 month 3 weeks (www.sciencedaily.com)

Children with heart defects may someday receive perfectly-matched new heart valves built using stem cells from their umbilical cord blood, according to research presented at the American Heart Association’s Scientific Sessions 2008.

12

Coaxing Injured Nerves to Regrow

piggy submitted, created time 2 months 1 day (sciencenow.sciencemag.org)

The adult central nervous system has only a limited ability to repair itself. That's why spinal cord injuries leave people permanently paralyzed. Now a study with mice finds that removing a particular signaling molecule in adult neurons restores their ability to regenerate damaged axons, the long extensions that convey signals from one neuron to another. The find potentially paves the way for repairing spinal cords and other nervous system injuries

15

Testicles could provide "ethical" stem cells

sea-maid submitted, created time 2 months 3 weeks (www.newscientist.com)

This article provides more information about last week's announcement that researchers have found a form of adult stem cells that appear to be as versatile as embryonic cells ...in men's testicles.

A team out of the University of Tubingen in Germany managed to convert spermatagonial cells into skin, gut structures, cartilage, bone, muscle, and neurons, quite an accomplishment. Some of their colleagues are enthusiastic. Robert Lanza of Advanced Cell Technology in Massachusetts (U.S

8

Stem cells from testicles offer an alternative to embryos

jerry submitted, created time 2 months 4 weeks (ap.google.com)

Cells taken from men's testicles seem as versatile as the stem cells derived from embryos, researchers reported Wednesday in what may be yet another new approach in a burgeoning scientific field. The downside? Because of their source, these cells could only be used for regenerative medicine in male patients, not in female ones.

The study involved twenty-two samples from men aged seventeen to eighty-one. All of them men were undergoing treatments for other reasons

7

Regenerative medicine may have just found a shortcut

sea-maid submitted, created time 3 months 1 day (www.nature.com)

Moving from one differentiated cell type from another may not always require a stopover in an undifferentiated state. This paper shows an alternative route to a differentiated state, which may have serious applications in regenerative medicine and provide real-world applications for human embryonic stem cells.

8

Stem cells on the battlefield: the military takes interest in transfusions

Darkfrog submitted, created time 3 months 4 weeks (www.nytimes.com)

We've discussed these several issues with other articles, but the Times stitches them together nicely. When we talk about stem cells, people tend to think of old men with Alzheimer's. When we talk about regenerative medicine, people tend to think of regrowing lost limbs. But the fact that companies--and the University of Ohio--are trying to hammer the kinks out of turning embryonic stem cells into red blood cells. DARPA is taking a deep interest, hoping for a way to turn progenitor cells into blood cells ont he battlefield

9

Stem cells from menstrual blood save limbs

sea-maid submitted, created time 4 months 2 weeks (www.newscientist.com)

Stem cells derived from human menstrual blood have, in mice, prevented limbs with restricted blood flow from withering. Trials in humans facing amputations are expected to start next year.

10

They're calling it "biological alchemy": induced stem cells proliferate

sea-maid submitted, created time 6 months 18 hours (www.newscientist.com)

CALL it biological alchemy: specialist pancreatic cells that secrete digestive enzymes have been converted directly into insulin-producing beta cells. Meanwhile, epithelial cells from the back of the eye have been coaxed into becoming a versatile, new type of stem cell.

Both advances, reported last week in Philadelphia, Pennsylvania, at the annual meeting of the International Society for Stem Cell Research (ISSCR), may take us closer to a "regenerative" approach to repairing damaged tissue

10

The military AFIRMs regenerative medicine

Darkfrog submitted, created time 6 months 1 week (www.popsci.com)

As of this past March, thirty different research institutions have joined to become the Armed Forces Institute of Regenerative Medicine (AFIRM). With $250-million in funding, they plan to expand ideas like the "pixie dust" limb regrowth method that was mentioned on DiscoveR8 a few months back. Most interestingly, there are plans for a handheld spritzer that would spray keratinocytes directly onto burns and wounds.

I followed the links to this one. A few blogs wrote articles based on this one, but focusing on just the burn sprayer, which they've nicknamed the "stem cell gun

10

Scientists use "biological alchemy" to convert one cell type into another

sea-maid submitted, created time 6 months 2 weeks (www.telegraph.co.uk)

Biological alchemy has been used to convert one cell type into another kind that could be used to repair a body damaged by accident or disease, marking a new approach to regenerative medicine that does away with the use of stem cells and embryos.

10

Nerve stem cells coaxed into working nerve cells

Darkfrog submitted, created time 6 months 3 weeks (www.medicalnewstoday.com)

Researchers at the UT Southwestern Medical Center have found a number of small compounds that stimulate nerve stem cells to develop into nerve cells. They synthesized a version that they are calling isoxazole-9, or ISX-9. This compound seems to have applications in nerve damage and brain cancer chemotheryapy.

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