Selenium may prevent high-risk bladder cancer

piggy submitted, created time 4 weeks 2 days (www.eurekalert.org)

A study published in the December issue of Cancer Prevention Research, a journal of the American Association for Cancer Research, suggests that selenium, a trace mineral found in grains, nuts and meats, may aid in the prevention of high-risk bladder cancer.

Researchers from Dartmouth Medical School compared selenium levels in 767 individuals newly diagnosed with bladder cancer to the levels of 1,108 individuals from the general population. Findings showed an inverse association between selenium and bladder cancer among women, some smokers and those with p53 positive bladder cancer

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Exposure to PCBs decreases likelihood of giving birth to boys

kavin submitted, created time 5 months 2 weeks (www.ehjournal.net)

Women exposed to high levels of PCBs (polychlorinated biphenyls - a group of banned environmental pollutants) are less likely to give birth to male children.

A study published today in BioMed Central's open access journal Environmental Health found that among women from the San Francisco Bay Area, those exposed to higher levels of PCBs during the 50s and 60s, were significantly more likely to give birth to female children

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Selenium status alters tumour differentiation but not incidence or latency of pancreatic adenocarcinomas in Ela-TGF- p53+/– mice

jiangyun submitted, created time 1 year 4 months (carcin.oxfordjournals.org)

Pancreatic carcinoma has so far not been tested as an end point in such studies. We thus investigated the influence of supplemental nutritive selenium on pancreatic carcinogenesis in selenium deficient animals by use of a genetically defined disease model. Over a period of 800 days, all animals (n = 131) in the study developed tumours.

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Selenium Supplements May Increase the Risk of Type 2 Diabetes

bianjie submitted, created time 1 year 5 months (www.buffalo.edu)

Selenium, an antioxidant included in multivitamin tablets thought to have a possible protective effect against the development of type 2 diabetes, may actually increase the risk of developing the disease, an analysis by researchers at the University at Buffalo has shown.

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Targeting the Nrf2-Prx1 Pathway with Selenium to Enhance the Efficacy and Selectivity of Cancer Therapy

Serum Selenium and Diabetes in U.S. Adults

alpha submitted, created time 1 year 8 months (care.diabetesjournals.org)

"In a probability sample of the U.S. population, high serum selenium levels were positively associated with the prevalence of diabetes. Until findings from prospective studies and randomized controlled trials are available, selenium intake, including selenium supplementation, should not be recommended for primary or secondary diabetes prevention in populations with adequate selenium status such as the U.S. population. "

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Selenium loss linked to cognitive decline in aged

amber submitted, created time 1 year 11 months (www.sciam.com)

The results of a new study conducted by researchers in France suggest that selenium levels decrease with age, which may contribute to a loss of neurological abilities in the elderly.

Because "oxidative stress" is one cause of brain impairment, selenium, which is an antioxidant, may protect against cognitive decline. Cognitive function refers to how the brain processes information, and includes functions such as comprehension, decision-making, memory and learning, abilities that may be lost in dementia

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